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Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study

BMJ, 2010-03, Vol.340 (mar18 3), p.c1279-c1279 [Periódico revisado por pares]

England: British Medical Journal Publishing Group

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Título:
Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study
Assuntos: Adolescent ; Adult ; Australia - epidemiology ; Child Health ; Clinical outcomes ; Cohort Studies ; Critical Care - statistics & numerical data ; Critical Illness ; Epidemiologic Studies ; Female ; Humans ; Infectious Diseases ; Influenza A Virus, H1N1 Subtype ; Influenza, Human - complications ; Influenza, Human - epidemiology ; Intensive care ; Neonatal and Paediatric Intensive Care ; Neonatal Health ; New Zealand - epidemiology ; Patient admissions ; Postpartum depression ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Outcome ; Prenatal Care - statistics & numerical data ; Reproductive Medicine ; Risk Factors ; Swine flu ; Young Adult
É parte de: BMJ, 2010-03, Vol.340 (mar18 3), p.c1279-c1279
Notas: local:bmj;340/mar18_3/c1279
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PMID:20299694
ObjectType-Article-1
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Descrição: Objective To describe the epidemiology of 2009 A/H1N1 influenza in critically ill pregnant women.Design Population based cohort study.Setting All intensive care units in Australia and New Zealand.Participants All women with 2009 H1N1 influenza who were pregnant or recently post partum and admitted to an intensive care unit in Australia or New Zealand between 1 June and 31 August 2009.Main outcome measures Maternal and neonatal mortality and morbidity.Results 64 pregnant or postpartum women admitted to an intensive care unit had confirmed 2009 H1N1 influenza. Compared with non-pregnant women of childbearing age, pregnant or postpartum women with 2009 H1N1 influenza were at increased risk of admission to an intensive care unit (relative risk 7.4, 95% confidence interval 5.5 to 10.0). This risk was 13-fold greater (13.2, 9.6 to 18.3) for women at 20 or more weeks’ gestation. At the time of admission to an intensive care unit, 22 women (34%) were post partum and two had miscarried. 14 women (22%) gave birth during their stay in intensive care and 26 (41%) were discharged from an intensive care unit with ongoing pregnancy. All subsequently delivered. 44 women (69%) were mechanically ventilated. Of these, nine (14%) were treated with extracorporeal membrane oxygenation. Seven women (11%) died. Of 60 births after 20 weeks’ gestation, four were stillbirths and three were infant deaths. 22 (39%) of the liveborn babies were preterm and 32 (57%) were admitted to a neonatal intensive care unit. Of 20 babies tested, two were positive for the 2009 H1N1 virus.Conclusions Pregnancy is a risk factor for critical illness related to 2009 H1N1 influenza, which causes maternal and neonatal morbidity and mortality.
Editor: England: British Medical Journal Publishing Group
Idioma: Inglês

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Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study

England: British Medical Journal Publishing Group

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