N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes

Fell, Matthew J ; Witkin, Jeffrey M ; Falcone, Julie F ; Katner, Jason S ; Perry, Kenneth W ; Hart, John ; Rorick-Kehn, Linda ; Overshiner, Carl D ; Rasmussen, Kurt ; Chaney, Stephen F ; Benvenga, Mark J ; Li, Xia ; Marlow, Deanna L ; Thompson, Linda K ; Luecke, Susan K ; Wafford, Keith A ; Seidel, Wesley F ; Edgar, Dale M ; Quets, Anne T ; Felder, Christian C ; Wang, XuShan ; Heinz, Beverly A ; Nikolayev, Alexander ; Kuo, Ming-Shang ; Mayhugh, Daniel ; Khilevich, Albert ; Zhang, Deyi ; Ebert, Philip J ; Eckstein, James A ; Ackermann, Bradley L ; Swanson, Steven P ; Catlow, John T ; Dean, Robert A ; Jackson, Kimberley ; Tauscher-Wisniewski, Sitra ; Marek, Gerard J ; Schkeryantz, Jeffrey M ; Svensson, Kjell A

The Journal of pharmacology and experimental therapeutics, 2011-01, Vol.336 (1), p.165-177 [Periódico revisado por pares]

United States

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