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A prospective, randomized comparison of pain, inflammatory response, and short-term outcomes between single port and laparoscopic cholecystectomy

Luna, Renato A. ; Nogueira, Daniel B. ; Varela, Pablo S. ; de O. Rodrigues Neto, Eduardo ; Norton, Maria Júlia R. ; do Carmo B. Ribeiro, Luciana ; Peixoto, Agatha M. ; de Mendonça, Yara L. ; Bendet, Isidro ; Fiorelli, Rossano A. ; Dolan, James P.

Surgical endoscopy, 2013-04, Vol.27 (4), p.1254-1259 [Periódico revisado por pares]

New York: Springer-Verlag

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Título:
A prospective, randomized comparison of pain, inflammatory response, and short-term outcomes between single port and laparoscopic cholecystectomy
Autor: Luna, Renato A. ; Nogueira, Daniel B. ; Varela, Pablo S. ; de O. Rodrigues Neto, Eduardo ; Norton, Maria Júlia R. ; do Carmo B. Ribeiro, Luciana ; Peixoto, Agatha M. ; de Mendonça, Yara L. ; Bendet, Isidro ; Fiorelli, Rossano A. ; Dolan, James P.
Assuntos: Abdominal Surgery ; Adult ; Aged ; Aged, 80 and over ; Analgesics ; Body mass index ; Cholecystectomy ; Cholecystectomy, Laparoscopic - adverse effects ; Cholecystectomy, Laparoscopic - methods ; Cytokines ; Endoscopy ; Female ; Gallbladder ; Gastroenterology ; Gynecology ; Hepatology ; Humans ; Inflammation - etiology ; Laparoscopy ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Pain ; Pain, Postoperative - etiology ; Patients ; Proctology ; Prospective Studies ; Recovery (Medical) ; Severity of Illness Index ; Surgery ; Surgical outcomes ; Time Factors ; Treatment Outcome ; Young Adult
É parte de: Surgical endoscopy, 2013-04, Vol.27 (4), p.1254-1259
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
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Descrição: Background The purpose of this study was to compare the postoperative inflammatory response and severity of pain between single-incision laparoscopic surgery (SILS) cholecystectomy and conventional laparoscopic cholecystectomy (LC). Methods Two groups of 20 patients were prospectively randomized to either conventional LC or SILS cholecystectomy. Serum interleukin-6 (IL-6) levels were assayed before surgery, at 4–6 h, and at 18–24 h after the procedure. Serum C-reactive protein (CRP) levels also were assayed at 18–24 h after surgery. Pain was measured at each of three time points after surgery using the visual analogue scale (VAS). The number of analgesia doses administered in the first 24 h after the procedure also was recorded and 30-day surgical outcomes were documented. Results The groups had equivalent body mass index (BMI), age, and comorbidity distribution. Peak IL-6 levels occurred 4–6 h after surgery, and the median level was 12.8 pg/ml in the LC and 8.9 pg/ml in the SILS group ( p = 0.5). The median CRP level before discharge was 1.6 mg/dl in the LC and 1.9 mg/dl in the SILS group ( p = 0.38). There was no difference in either analgesic use or pain intensity as measured by the VAS between the two groups ( p = 0.72). The length of the surgical procedure was significantly longer in the SILS group ( p < 0.001). No intraoperative complications occurred in either group. Conclusions Single-incision laparoscopic surgery does not significantly reduce systemic inflammatory response, postoperative pain, or analgesic use compared with LC.
Editor: New York: Springer-Verlag
Idioma: Inglês

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A prospective, randomized comparison of pain, inflammatory response, and short-term outcomes between single port and laparoscopic cholecystectomy

Luna, Renato A. ; Nogueira, Daniel B. ; Varela, Pablo S. ; de O. Rodrigues Neto, Eduardo ; Norton, Maria Júlia R. ; do Carmo B. Ribeiro, Luciana ; Peixoto, Agatha M. ; de Mendonça, Yara L. ; Bendet, Isidro ; Fiorelli, Rossano A. ; Dolan, James P.

New York: Springer-Verlag

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