skip to main content
Idioma:
Tipo de recurso Mostra resultados com: Mostra resultados com: Índice

Serum Potassium Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients

Charat Thongprayoon ; Wisit Cheungpasitporn ; Sorkko Thirunavukkarasu ; Tananchai Petnak ; Api Chewcharat ; Tarun Bathini ; Saraschandra Vallabhajosyula ; Michael A Mao ; Stephen B. Erickson

Medicina (Kaunas, Lithuania), 2020-05, Vol.56 (236), p.236 [Periódico revisado por pares]

MDPI AG

Texto completo disponível

Citações Citado por
  • Título:
    Serum Potassium Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients
  • Autor: Charat Thongprayoon ; Wisit Cheungpasitporn ; Sorkko Thirunavukkarasu ; Tananchai Petnak ; Api Chewcharat ; Tarun Bathini ; Saraschandra Vallabhajosyula ; Michael A Mao ; Stephen B. Erickson
  • Assuntos: discharge ; electrolytes ; hyperkalemia ; hypokalemia ; mortality ; potassium
  • É parte de: Medicina (Kaunas, Lithuania), 2020-05, Vol.56 (236), p.236
  • Descrição: Background and Objectives: The optimal range of serum potassium at hospital discharge is unclear. The aim of this study was to assess the relationship between discharge serum potassium levels and one-year mortality in hospitalized patients. Materials and Methods: All adult hospital survivors between 2011 and 2013 at a tertiary referral hospital, who had available admission and discharge serum potassium data, were enrolled. End-stage kidney disease patients were excluded. Discharge serum potassium was defined as the last serum potassium level measured within 48 hours prior to hospital discharge and categorized into ≤ 2.9, 3.0–3.4, 3.5–3.9, 4.0–4.4, 4.5–4.9, 5.0–5.4 and ≥ 5.5 mEq/L. A Cox proportional hazards analysis was performed to assess the independent association between discharge serum potassium and one-year mortality after hospital discharge, using the discharge potassium range of 4.0–4.4 mEq/L as the reference group. Results: Of 57,874 eligible patients, with a mean discharge serum potassium of 4.1 ± 0.4 mEq/L, the estimated one-year mortality rate after discharge was 13.2%. A U-shaped association was observed between discharge serum potassium and one-year mortality, with the nadir mortality in the discharge serum potassium range of 4.0–4.4 mEq/L. After adjusting for clinical characteristics, including admission serum potassium, both discharge serum potassium ≤ 3.9 mEq/L and ≥ 4.5 mEq/L were significantly associated with increased one-year mortality, compared with the discharge serum potassium of 4.0–4.4 mEq/L. Stratified analysis based on admission serum potassium showed similar results, except that there was no increased risk of one-year mortality when discharge serum potassium was ≤ 3.9 mEq/L in patients with an admission serum potassium of ≥ 5.0 mEq/L. Conclusion: The association between discharge serum potassium and one-year mortality after hospital discharge had a U-shaped distribution and was independent of admission serum potassium. Favorable survival outcomes occurred when discharge serum potassium was strictly within the range of 4.0–4.4 mEq/L.
  • Editor: MDPI AG
  • Idioma: Inglês
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.