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Application of a cost-effectiveness analysis of pathogen-specific vaccines against gastroenteritis to a military population in a developing country setting

Ballard, Sarah-Blythe ; Tallant, Aaron ; Guerra, Rosio G. ; Quigley, Dawn ; Stiegmann, Regan ; Mirelman, Andrew J. ; Riddle, Mark S. ; Gilman, Robert H.

Vaccine, 2020-02, Vol.38 (10), p.2292-2297 [Periódico revisado por pares]

Netherlands: Elsevier Ltd

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Título:
Application of a cost-effectiveness analysis of pathogen-specific vaccines against gastroenteritis to a military population in a developing country setting
Autor: Ballard, Sarah-Blythe ; Tallant, Aaron ; Guerra, Rosio G. ; Quigley, Dawn ; Stiegmann, Regan ; Mirelman, Andrew J. ; Riddle, Mark S. ; Gilman, Robert H.
Assuntos: Adult ; Aerospace medicine ; Armed forces ; Campylobacter ; Cost analysis ; Cost estimates ; Cost-Benefit Analysis ; Cost-effectiveness analysis ; Developing Countries ; Diarrhea ; Disease ; Economic analysis ; Economic models ; Gastroenteritis ; Gastroenteritis - economics ; Gastroenteritis - prevention & control ; Humans ; Income ; LDCs ; Low income groups ; Low- and middle-income countries ; Military ; Military Personnel ; Models, Economic ; Pathogens ; Peru ; Population ; Sensitivity analysis ; Shigella ; Surveillance ; Vaccine ; Vaccines ; Vaccines - economics ; Working groups
É parte de: Vaccine, 2020-02, Vol.38 (10), p.2292-2297
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Fabiola Aliaga-Colquechagua, Daniel G. Bausch, David L. Blazes, Caryn Bern, Lilia Cabrera, Maritza Calderon, Briasaida Cordova-Rafael, Kristen Heitzinger, Mary Carol Jennings, Margaret Kosek, Luis Loayza, C. Giannina Luna, Holger Mayta, Rina Meza, Karen Neira, Monica Pajuelo, Karen Parreira, Simon Pollett, Jose Quispe, Laura Rappoport, Erik J. Reaves, Claudio Rocha, Jessica Rothstein, Mayuko Saito, Gerardo Sanchez, Maria E. Silva, Mark P. Simons, Hannah E. Steinberg, Drake H. Tilley, Manuela Verastegui.
Descrição: •Vaccine cost-effectiveness modeling can inform LMIC military health policies.•Enteropathogen vaccines may be cost-effective for special LMIC adult populations.•Shigella and norovirus vaccines appear cost-effective for Peruvian troops. Vaccine implementation planning in low- and middle-income countries (LMIC) often focuses on children without considering special adult populations. We adapted an economic model developed by the United States Department of Defense (DoD) to evaluate the cost-effectiveness of vaccine acquisition strategies for Campylobacter-, ETEC-, Shigella-, and norovirus-associated gastroenteritis. We compared implementation costs with current medical management in the Peruvian armed forces, a special population of low- and middle-income (LMIC) adults with a high incidence of infectious gastroenteritis. Pathogen-specific vaccine implementation resulted in calculated cost-effectiveness ratio (CER) per duty day lost averted (CERDDL) of $13,741; $1,272; $301; and $803, and a CER per diarrhea day averted of $2,130; $215; $51; and $199 for Campylobacter, ETEC, Shigella, and norovirus, respectively. These estimates compare favorably to CERDDL estimates from high-income military population and suggest that implementing vaccines gastroenteritis may be cost-effective in the Peruvian military population.
Editor: Netherlands: Elsevier Ltd
Idioma: Inglês

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Application of a cost-effectiveness analysis of pathogen-specific vaccines against gastroenteritis to a military population in a developing country setting

Ballard, Sarah-Blythe ; Tallant, Aaron ; Guerra, Rosio G. ; Quigley, Dawn ; Stiegmann, Regan ; Mirelman, Andrew J. ; Riddle, Mark S. ; Gilman, Robert H.

Netherlands: Elsevier Ltd

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