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Primary results of the brazilian registry of atherothrombotic disease (NEAT)

de Barros E Silva, Pedro G M ; do Nascimento, Charlene Troiani ; Pedrosa, Rodrigo Pinto ; Nakazone, Marcelo Arruda ; do Nascimento, Michel Ulloffo ; de Araújo Melo, Leiliandry ; Júnior, Osvaldo Lourenço Silva ; Zimmermann, Sérgio Luiz ; de Melo, Rodrigo Morel Vieira ; Bergo, Ricardo Reinaldo ; Precoma, Dalton Bertolim ; Tramujas, Lucas ; Lima, Eduardo Gomes ; Dantas, João Miguel Malta ; do Amaral Baruzzi, Antônio Cláudio ; Flumignan, Ronald Luiz Gomes ; de Oliveira Paiva, Maria Sanali Moura ; Gowdak, Luís Henrique Wolff ; de Carvalho, Priscila Nasser ; de Figueiredo Neto, José Albuquerque ; Silvestre, Odilson Marcos ; Fioranelli, Alexandre ; Vieira, Ricardo D 'Oliveira ; Horak, Ana Clara Peneluppi ; Miyada, Debora Harumi Kodama ; Kojima, Flávia Cristina Soares ; de Oliveira, Júlia Souza ; de Oliveira Silva, Leila ; Pavanello, Ricardo ; Ramacciotti, Eduardo ; Lopes, Renato D

Scientific reports, 2024-02, Vol.14 (1), p.4222-4222, Article 4222 [Periódico revisado por pares]

England: Nature Publishing Group

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Título:
Primary results of the brazilian registry of atherothrombotic disease (NEAT)
Autor: de Barros E Silva, Pedro G M ; do Nascimento, Charlene Troiani ; Pedrosa, Rodrigo Pinto ; Nakazone, Marcelo Arruda ; do Nascimento, Michel Ulloffo ; de Araújo Melo, Leiliandry ; Júnior, Osvaldo Lourenço Silva ; Zimmermann, Sérgio Luiz ; de Melo, Rodrigo Morel Vieira ; Bergo, Ricardo Reinaldo ; Precoma, Dalton Bertolim ; Tramujas, Lucas ; Lima, Eduardo Gomes ; Dantas, João Miguel Malta ; do Amaral Baruzzi, Antônio Cláudio ; Flumignan, Ronald Luiz Gomes ; de Oliveira Paiva, Maria Sanali Moura ; Gowdak, Luís Henrique Wolff ; de Carvalho, Priscila Nasser ; de Figueiredo Neto, José Albuquerque ; Silvestre, Odilson Marcos ; Fioranelli, Alexandre ; Vieira, Ricardo D 'Oliveira ; Horak, Ana Clara Peneluppi ; Miyada, Debora Harumi Kodama ; Kojima, Flávia Cristina Soares ; de Oliveira, Júlia Souza ; de Oliveira Silva, Leila ; Pavanello, Ricardo ; Ramacciotti, Eduardo ; Lopes, Renato D
Assuntos: Aged ; Blood pressure ; Brazil - epidemiology ; Cardiovascular disease ; Cardiovascular diseases ; Cholesterol ; Clinical medicine ; Coronary Artery Disease - drug therapy ; Disease prevention ; Female ; Guideline adherence ; Health risks ; Heart attacks ; Humans ; Low density lipoprotein ; Male ; Middle Aged ; Multicenter Studies as Topic ; Observational studies ; Observational Studies as Topic ; Patients ; Peripheral Arterial Disease - epidemiology ; Prevention ; Prospective Studies ; Registries ; Research centers ; Risk Factors ; Rivaroxaban - therapeutic use
É parte de: Scientific reports, 2024-02, Vol.14 (1), p.4222-4222, Article 4222
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: There is limited contemporary prospective real-world evidence of patients with chronic arterial disease in Latin America. The Network to control atherothrombosis (NEAT) registry is a national prospective observational study of patients with known coronary (CAD) and/or peripheral arterial disease (PAD) in Brazil. A total of 2,005 patients were enrolled among 25 sites from September 2020 to March 2022. Patient characteristics, medications and laboratorial data were collected. Primary objective was to assess the proportion of patients who, at the initial visit, were in accordance with good medical practices (domains) for reducing cardiovascular risk in atherothrombotic disease. From the total of patients enrolled, 2 were excluded since they did not meet eligibility criteria. Among the 2,003 subjects included in the analysis, 55.6% had isolated CAD, 28.7% exclusive PAD and 15.7% had both diagnoses. Overall mean age was 66.3 (± 10.5) years and 65.7% were male patients. Regarding evidence-based therapies (EBTs), 4% were not using any antithrombotic drug and only 1.5% were using vascular dose of rivaroxaban (2.5 mg bid). Only 0.3% of the patients satisfied all the domains of secondary prevention, including prescription of EBTs and targets of body-mass index, blood pressure, LDL-cholesterol, and adherence of lifestyle recommendations. The main barrier for prescription of EBTs was medical judgement. Our findings highlight that the contemporary practice does not reflect a comprehensive approach for secondary prevention and had very low incorporation of new therapies in Brazil. Large-scale populational interventions addressing these gaps are warranted to improve the use of evidence-based therapies and reduce the burden of atherothrombotic disease.ClinicalTrials.gov NCT04677725.
Editor: England: Nature Publishing Group
Idioma: Inglês

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Primary results of the brazilian registry of atherothrombotic disease (NEAT)

England: Nature Publishing Group

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