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Association of Serum Ferritin Level with Risk of Incident Abnormal Glucose Metabolism in Southwestern China: a Prospective Cohort Study

Zhou, Fangli ; Zhao, Zhuoxian ; Tian, Li ; Zheng, Tianpeng ; Gao, Yun ; Chen, Tao ; Yan, Fangfang ; Tian, Haoming

Biological trace element research, 2016-01, Vol.169 (1), p.27-33 [Periódico revisado por pares]

New York: Springer US

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Título:
Association of Serum Ferritin Level with Risk of Incident Abnormal Glucose Metabolism in Southwestern China: a Prospective Cohort Study
Autor: Zhou, Fangli ; Zhao, Zhuoxian ; Tian, Li ; Zheng, Tianpeng ; Gao, Yun ; Chen, Tao ; Yan, Fangfang ; Tian, Haoming
Assuntos: Adult ; alcohols ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Blood Pressure - physiology ; blood serum ; China - epidemiology ; Cohort Studies ; diabetes ; Diabetes Mellitus, Type 2 - epidemiology ; Female ; females ; ferritin ; Ferritins - blood ; Glucose ; Glucose - metabolism ; Glucose Metabolism Disorders - epidemiology ; homeostasis ; Humans ; Insulin Resistance ; Life Sciences ; Logistic Models ; Male ; males ; Metabolic disorders ; Metabolism ; Middle Aged ; Nutrition ; Oncology ; Prospective Studies ; regression analysis ; relative risk ; Risk Factors ; Trace elements ; triacylglycerols ; Triglycerides - blood ; Waist Circumference
É parte de: Biological trace element research, 2016-01, Vol.169 (1), p.27-33
Notas: http://dx.doi.org/10.1007/s12011-015-0393-5
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Descrição: This prospective cohort study aimed to analyze the association between serum ferritin levels and the risk of abnormal glucose metabolism (AGM) in Southwestern Chinese population. The 383 subjects who are aged ≥20 years and free of AGM at baseline between in 2007 and in 2008 were included in Southwestern China, and their baseline serum ferritin levels were measured. Among these subjects, 140 subjects were developed into AGM during the follow-up (2008–2012). In logistic regression models, the relative risk in the top versus that in the lowest quartile of serum ferritin levels was 2.86 (p = 0.013) in females and 3.50 (p = 0.029) in males after adjusting the age, gender, family history of diabetes, current smoking, and alcohol; however, serum ferritin levels were not significantly associated with incident of AGM after controlling for metabolic factors (waist circumference, systolic pressure (SBP), triglyceride (TG), and homeostasis model assessment formula insulin resistance (HOMA-IR)). Elevated serum ferritin levels are associated with AGM but not an independent risk factor.
Editor: New York: Springer US
Idioma: Inglês

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Association of Serum Ferritin Level with Risk of Incident Abnormal Glucose Metabolism in Southwestern China: a Prospective Cohort Study

Zhou, Fangli ; Zhao, Zhuoxian ; Tian, Li ; Zheng, Tianpeng ; Gao, Yun ; Chen, Tao ; Yan, Fangfang ; Tian, Haoming

New York: Springer US

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