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Assessment of problematic severe asthma in children

LØDRUP CARLSEN, K. C ; HEDLIN, G ; POHUNEK, P ; PEDERSEN, S ; PIACENTINI, G. L ; MIDDELVELD, R. J. M ; BUSH, A ; WENNERGREN, G ; DE BENEDICTIS, F. M ; DE JONGSTE, J. C ; BARALDI, E ; PEDROLETTI, C ; BARBATO, A ; MALMSTRÖM, K

The European respiratory journal, 2011-02, Vol.37 (2), p.432-440 [Periódico revisado por pares]

Leeds: Maney

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Título:
Assessment of problematic severe asthma in children
Autor: LØDRUP CARLSEN, K. C ; HEDLIN, G ; POHUNEK, P ; PEDERSEN, S ; PIACENTINI, G. L ; MIDDELVELD, R. J. M ; BUSH, A ; WENNERGREN, G ; DE BENEDICTIS, F. M ; DE JONGSTE, J. C ; BARALDI, E ; PEDROLETTI, C ; BARBATO, A ; MALMSTRÖM, K
Assuntos: Anti-Asthmatic Agents ; Anti-Asthmatic Agents - therapeutic use ; Asthma ; Asthma - diagnosis ; Asthma - drug therapy ; Asthma - physiopathology ; Biological and medical sciences ; Bronchial Hyperreactivity ; Bronchial Hyperreactivity - diagnosis ; Bronchial Hyperreactivity - drug therapy ; Bronchial Hyperreactivity - epidemiology ; Child ; Chronic obstructive pulmonary disease, asthma ; Comorbidity ; diagnosis ; drug therapy ; epidemiology ; Humans ; Immunologi inom det medicinska området ; Immunology in the medical area ; Medical sciences ; Medicin och hälsovetenskap ; Other Social Sciences not elsewhere specified ; physiopathology ; Pneumology ; Respiratory Function Tests ; Rhinitis ; Rhinitis - diagnosis ; Rhinitis - drug therapy ; Rhinitis - epidemiology ; Severity of Illness Index ; therapeutic use ; Treatment Outcome ; Övrig annan samhällsvetenskap
É parte de: The European respiratory journal, 2011-02, Vol.37 (2), p.432-440
Descrição: Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients.
Editor: Leeds: Maney
Idioma: Inglês

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Assessment of problematic severe asthma in children

LØDRUP CARLSEN, K. C ; HEDLIN, G ; POHUNEK, P ; PEDERSEN, S ; PIACENTINI, G. L ; MIDDELVELD, R. J. M ; BUSH, A ; WENNERGREN, G ; DE BENEDICTIS, F. M ; DE JONGSTE, J. C ; BARALDI, E ; PEDROLETTI, C ; BARBATO, A ; MALMSTRÖM, K

Leeds: Maney

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