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Influence of desensitizing and anti-erosive toothpastes on dentine permeability: An in vitro study

João-Souza, Samira Helena ; Scaramucci, Tais ; Bühler Borges, Alessandra ; Lussi, Adrian ; Saads Carvalho, Thiago ; Corrêa Aranha, Ana Cecília

Journal of dentistry, 2019-10, Vol.89, p.103176-103176, Article 103176 [Periódico revisado por pares]

England: Elsevier Ltd

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Título:
Influence of desensitizing and anti-erosive toothpastes on dentine permeability: An in vitro study
Autor: João-Souza, Samira Helena ; Scaramucci, Tais ; Bühler Borges, Alessandra ; Lussi, Adrian ; Saads Carvalho, Thiago ; Corrêa Aranha, Ana Cecília
Assuntos: Abrasion ; Acetic acid ; Arginine ; Calcium carbonate ; Calcium phosphates ; Calcium silicates ; Chitosan ; Chlorides ; Citric acid ; Conductance ; Dental abrasion ; Dental erosion ; Dentifrices ; Dentin ; Dentin Desensitizing Agents - pharmacology ; Dentin Permeability - drug effects ; Dentin Sensitivity - drug therapy ; Dentine permeability ; Dentistry ; Desensitization ; Erosion ; Ethylenediaminetetraacetic acids ; Exposure ; Fluoridation ; Fluorides - pharmacology ; Humans ; Hydraulic conductance ; Hydraulics ; Hypersensitivity ; Molar ; Molars ; Pain ; Permeability ; Potassium ; Potassium nitrate ; Resistance ; Saliva ; Slurries ; Sodium ; Sodium Fluoride ; Sodium phosphate ; Stannous chloride ; Stannous fluoride ; Strontium ; Studies ; Submerging ; Teeth ; Tin chloride ; Toothbrushes ; Toothpaste ; Toothpastes ; Toothpastes - pharmacology ; Treatment Outcome ; Tubule occlusion
É parte de: Journal of dentistry, 2019-10, Vol.89, p.103176-103176, Article 103176
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SourceType-Scholarly Journals-1
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Descrição: This study analyzed the effect of desensitizing and/or anti-erosive toothpastes on dentine permeability. One-mm dentin discs were prepared from human molars and exposed to EDTA solution (5 min, 17%). Initial dentine permeability was measured, under constant pressure. Specimens were randomly allocated into 10 groups: four anti-erosive toothpastes (calcium silicate + sodium phosphate, potassium nitrate, stannous chloride + chitosan, oligopeptide-104); four desensitizing toothpastes (arginine + calcium carbonate, calcium sodium phosphosilicate, strontium acetate, stannous fluoride); and two controls (regular fluoridated toothpaste, and human saliva). They were submitted to a 5-day erosion-abrasion cycling model. Erosion consisted of immersion in citric acid (2 min, 0.3%, natural pH ˜ 2.6, 4x/day), followed by 1 h exposure to human saliva. Specimens were brushed for 15 s (2 N, 45 strokes) with the toothpaste slurries (total exposure time of 2 min). After 5 cycles, the final dentine permeability was determined. Dentine permeability change was calculated as a percentage of the initial hydraulic conductance (%Lp). Data were analyzed with one-way ANOVA and Tukey tests (α=0.05). The toothpastes calcium silicate + sodium phosphate and potassium nitrate, showed significant decrease in %Lp, with no difference between them. The regular fluoridated toothpaste also decreased the %Lp, not differing from potassium nitrate. No desensitizing toothpaste showed change in %Lp. Human saliva, oligopeptide-104 and stannous chloride + chitosan presented significant increase in %Lp, without difference between them. Calcium silicate + sodium phosphate, potassium nitrate, and the regular fluoridated toothpaste decreased dentine permeability, whereas the desensitizing toothpastes tested did not. Toothpastes had distinct impacts on dentine permeability, which may reflect a variable effect on the treatment of dentine hypersensitivity. Within the limitations of a laboratory-based study, toothpastes with an anti-erosive claim could also be effective in reducing the pain in dentine hypersensitivity.
Editor: England: Elsevier Ltd
Idioma: Inglês

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Influence of desensitizing and anti-erosive toothpastes on dentine permeability: An in vitro study

João-Souza, Samira Helena ; Scaramucci, Tais ; Bühler Borges, Alessandra ; Lussi, Adrian ; Saads Carvalho, Thiago ; Corrêa Aranha, Ana Cecília

England: Elsevier Ltd

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