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Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis

Ferrazzi, E ; Frigerio, L ; Savasi, V ; Vergani, P ; Prefumo, F ; Barresi, S ; Bianchi, S ; Ciriello, E ; Facchinetti, F ; Gervasi, MT ; Iurlaro, E ; Kustermann, A ; Mangili, G ; Mosca, F ; Patanè, L ; Spazzini, D ; Spinillo, A ; Trojano, G ; Vignali, M ; Villa, A ; Zuccotti, GV ; Parazzini, F ; Cetin, I

BJOG : an international journal of obstetrics and gynaecology, 2020-08, Vol.127 (9), p.1116-1121 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis
Autor: Ferrazzi, E ; Frigerio, L ; Savasi, V ; Vergani, P ; Prefumo, F ; Barresi, S ; Bianchi, S ; Ciriello, E ; Facchinetti, F ; Gervasi, MT ; Iurlaro, E ; Kustermann, A ; Mangili, G ; Mosca, F ; Patanè, L ; Spazzini, D ; Spinillo, A ; Trojano, G ; Vignali, M ; Villa, A ; Zuccotti, GV ; Parazzini, F ; Cetin, I
Assuntos: Adult ; Betacoronavirus ; Breast feeding ; Childbirth & labor ; Coronavirus Infections - diagnosis ; Coronavirus Infections - transmission ; COVID-19 ; delivery ; Delivery, Obstetric - adverse effects ; Female ; General Obstetrics ; Health risk assessment ; Humans ; Infant, Newborn ; Infections ; Infectious Disease Transmission, Vertical ; Italy ; Male ; Morbidity ; Neonates ; Pandemics ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - transmission ; Postpartum ; Pregnancy ; Pregnancy Complications, Infectious - diagnosis ; Pregnancy Complications, Infectious - virology ; Retrospective Studies ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; transmission ; Vagina ; Vagina - virology ; Womens health
É parte de: BJOG : an international journal of obstetrics and gynaecology, 2020-08, Vol.127 (9), p.1116-1121
Notas: https://vimeo.com/rcog/authorinsights16278
This article includes Author Insights, a video abstract available at
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Linked article: This article is commented on by JG Thornton. To view this mini commentary visit https://doi.org/10.1111/1471-0528.16308.
This article includes Author Insights, a video abstract available at https://vimeo.com/rcog/authorinsights16278
Descrição: Objective To report mode of delivery and immediate neonatal outcome in women infected with COVID‐19. Design Retrospective study. Setting Twelve hospitals in northern Italy. Participants Pregnant women with COVID‐19‐confirmed infection who delivered. Exposure COVID 19 infection in pregnancy. Methods SARS‐CoV‐2‐infected women who were admitted and delivered from 1 to 20 March 2020 were eligible. Data were collected from the clinical records using a standardised questionnaire on maternal general characteristics, any medical or obstetric co‐morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding. Main outcome and measures Data on mode of delivery and neonatal outcome. Results In all, 42 women with COVID‐19 delivered at the participating centres; 24 (57.1%, 95% CI 41.0–72.3) delivered vaginally. An elective caesarean section was performed in 18/42 (42.9%, 95% CI 27.7–59.0) cases: in eight cases the indication was unrelated to COVID‐19 infection. Pneumonia was diagnosed in 19/42 (45.2%, 95% CI 29.8–61.3) cases: of these, 7/19 (36.8%, 95% CI 16.3–61.6) required oxygen support and 4/19 (21.1%, 95% CI 6.1–45.6) were admitted to a critical care unit. Two women with COVID‐19 breastfed without a mask because infection was diagnosed in the postpartum period: their newborns tested positive for SARS‐Cov‐2 infection. In one case, a newborn had a positive test after a vaginal operative delivery. Conclusions Although postpartum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS‐Cov‐2 transmission to the newborn. Tweetable This study suggests that vaginal delivery may be associated with a low risk of intrapartum SARS‐Cov‐2 transmission to the newborn. Tweetable This study suggests that vaginal delivery may be associated with a low risk of intrapartum SARS‐Cov‐2 transmission to the newborn. This article includes Author Insights, a video available at https://vimeo.com/rcog/authorinsights16278
Editor: England: Wiley Subscription Services, Inc
Idioma: Inglês

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Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis

England: Wiley Subscription Services, Inc

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