Idioma:

Immunohistochemical localization of connective tissue growth factor in the rat central nervous system

Kondo, Yoichi ; Nakanishi, Tohru ; Takigawa, Masaharu ; Ogawa, Norio

Brain research, 1999-07, Vol.834 (1), p.146-151 [Revista revisada por pares]

London: Elsevier B.V

Texto completo disponible

Citas Citado por

Acciones

Título:
Immunohistochemical localization of connective tissue growth factor in the rat central nervous system
Autor: Kondo, Yoichi ; Nakanishi, Tohru ; Takigawa, Masaharu ; Ogawa, Norio
Materias: Anatomy ; Animals ; Astrocyte ; Biological and medical sciences ; Brain ; Central nervous system ; Central Nervous System - metabolism ; Cerebral Cortex - cytology ; Cerebral Cortex - metabolism ; Cerebral Ventricles - metabolism ; Connective Tissue Growth Factor ; Fundamental and applied biological sciences. Psychology ; Growth Substances - metabolism ; Immediate-Early Proteins ; Immunohistochemistry ; Intercellular Signaling Peptides and Proteins ; Male ; Pyramidal Cells - metabolism ; Rats ; Rats, Sprague-Dawley ; Spinal cord ; Spinal Cord - cytology ; Spinal Cord - metabolism ; Tissue Distribution - physiology ; Vertebrates: nervous system and sense organs
Es parte de: Brain research, 1999-07, Vol.834 (1), p.146-151
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
Descripción: Connective tissue growth factor (CTGF) is an immediate early growth-responsive gene but its distribution and significance in the central nervous system (CNS) are unknown. We investigated the distribution of CTGF-like immunoreactivity (CTGF-IR) in the rat CNS using a specific antiserum against CTGF oligopeptide. The majority of CTGF-IR was observed in astrocytes. Ependymal cells lining the wall of the cerebral ventricle and tanycytes lining the central canal of the spinal cord showed the strongest CTGF-IR, while there was a diffuse but weak signal in the gray matter of the spinal cord. CTGF-IR was also detected in the cytoplasm of a subpopulation of pyramidal neurons in the cerebral cortex. Our results showed that CTGF-IR is widely distributed in the CNS at both regional and cellular levels, suggesting a complex functional role in the CNS.
Editor: London: Elsevier B.V
Idioma: Inglés

Enlaces

Volver a la lista de resultados

Anterior Resultado 3 Siguiente Ir a la siguiente página

Realización: Logos de Redes Sociales:

Immunohistochemical localization of connective tissue growth factor in the rat central nervous system

Kondo, Yoichi ; Nakanishi, Tohru ; Takigawa, Masaharu ; Ogawa, Norio

London: Elsevier B.V

Buscando en bases de datos remotas, por favor espere