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Causality, mediation and time: a dynamic viewpoint

Aalen, Odd O. ; Røysland, Kjetil ; Gran, Jon Michael ; Ledergerber, Bruno

Journal of the Royal Statistical Society. Series A, Statistics in society, 2012-10, Vol.175 (4), p.831-861 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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Título:
Causality, mediation and time: a dynamic viewpoint
Autor: Aalen, Odd O. ; Røysland, Kjetil ; Gran, Jon Michael ; Ledergerber, Bruno
Assuntos: Applications ; Causal inference ; Causality ; Censorship ; Cohorts ; Communication ; Contrafactuals ; Differential equations ; Directed acyclic graphs ; Dynamic path analysis ; Dynamic tests ; Dynamical systems ; Dynamics ; Exact sciences and technology ; General topics ; Granger causality ; Graph representations ; Graphs ; Highly active antiretroviral therapy ; HIV ; HIV 1 ; Human immunodeficiency virus ; Inference ; Interventionism ; Local independence ; Manipulation ; Mathematics ; Mediation ; Original ; Probability and statistics ; RNA ; Sciences and techniques of general use ; Statistics ; Time
É parte de: Journal of the Royal Statistical Society. Series A, Statistics in society, 2012-10, Vol.175 (4), p.831-861
Notas: ark:/67375/WNG-FXGPFJ94-1
ArticleID:RSSA1030
istex:4AE18BB2E5797F7C37EE35A78318D1D8A9D5F197
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Reuse of this article is permitted in accordance with the terms and conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.
Descrição: Time dynamics are often ignored in causal modelling. Clearly, causality must operate in time and we show how this corresponds to a mechanistic, or system, understanding of causality. The established counterfactual definitions of direct and indirect effects depend on an ability to manipulate the mediator which may not hold in practice, and we argue that a mechanistic view may be better. Graphical representations based on local independence graphs and dynamic path analysis are used to facilitate communication as well as providing an overview of the dynamic relations 'at a glance'. The relationship between causality as understood in a mechanistic and in an interventionist sense is discussed. An example using data from the Swiss HIV Cohort Study is presented.
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

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Causality, mediation and time: a dynamic viewpoint

Aalen, Odd O. ; Røysland, Kjetil ; Gran, Jon Michael ; Ledergerber, Bruno

Oxford, UK: Blackwell Publishing Ltd

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