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Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates

Zhang, Xiao-Xiang ; Eden, Henry S. ; Chen, Xiaoyuan

Journal of controlled release, 2012-04, Vol.159 (1), p.2-13 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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Título:
Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates
Autor: Zhang, Xiao-Xiang ; Eden, Henry S. ; Chen, Xiaoyuan
Assuntos: Animals ; Biocompatibility ; Biological and medical sciences ; Cancer ; Controlled release ; drug carriers ; Drug delivery ; Drug Delivery Systems ; drugs ; General pharmacology ; Humans ; Ligands ; manufacturing ; Medical sciences ; nanomaterials ; Nanomedicine ; Nanoparticles - therapeutic use ; nanotechnology ; Neoplasms - drug therapy ; Neoplasms - metabolism ; Peptide Hydrolases - metabolism ; Peptides ; Peptides - therapeutic use ; Pharmaceutical technology. Pharmaceutical industry ; Pharmacology. Drug treatments ; Protease-responsive ; Proteinase ; proteinases ; Tumor targeting
É parte de: Journal of controlled release, 2012-04, Vol.159 (1), p.2-13
Notas: http://dx.doi.org/10.1016/j.jconrel.2011.10.023
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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Descrição: Peptides are attracting increasing attention as therapeutic agents, as the technologies for peptide development and manufacture continue to mature. Concurrently, with booming research in nanotechnology for biomedical applications, peptides have been studied as an important class of components in nanomedicine, and they have been used either alone or in combination with nanomaterials of every reported composition. Peptides possess many advantages, such as smallness, ease of synthesis and modification, and good biocompatibility. Their functions in cancer nanomedicine, discussed in this review, include serving as drug carriers, as targeting ligands, and as protease-responsive substrates for drug delivery. [Display omitted]
Editor: Kidlington: Elsevier B.V
Idioma: Inglês

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Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates

Zhang, Xiao-Xiang ; Eden, Henry S. ; Chen, Xiaoyuan

Kidlington: Elsevier B.V

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