Scientific opinion on the re‐evaluation of
silver
(
E
174) as food additive
ABCD PBi
Scientific opinion on the re‐evaluation of
silver
(
E
174) as food additive
Autor:
Oskarsson, Agneta
Assuntos:
Documents
;
E
174
;
Electron microscopy
;
Evaluation
;
Farmakologi och toxikologi
;
Food additives
;
Food analysis
;
food colour
;
Food safety
;
Ions
;
Microscopy
;
Nanoparticles
;
Particle size
;
Particle size distribution
;
Pharmacology and Toxicology
;
Risk assessment
;
Safety
;
Scanning electron microscopy
;
Silver
;
Size distribution
;
Toxicity
;
Toxicity testing
;
Transmission electron microscopy
É parte de:
EFSA journal, 2016-01, Vol.14 (1), p.n/a
Descrição:
The present opinion deals with the re‐evaluation of the safety of
silver
(
E
174) when used as a food additive.
Silver
in food additive
E
174 is present in its elemental form. The Panel noted that there are data gaps and concerns to be addressed to conduct a risk assessment with respect to the use of
silver
(
E
174): lack of data on toxicity studies on elemental
silver
or the food additive (
E
174); unknown particle size distribution of the food additive (
E
174); evidence of the release of
silver
ions from elemental
silver
, which may be of concern. However, the extent of the release of the
silver
ions is unknown in the case of
silver
(
E
174). The Panel concluded that the information available was insufficient to assess the safety of
silver
as food additive. The major issues included chemical identification an d characterisation of
silver
E
174 (e.g. quantity of nanoparticles and release of ionic
silver
) and similar information on the material used in the available toxicity studies. Therefore, the Panel concluded that the relevance of the available toxicological studies to the safety evaluation of silver as a food additive E 174 could not be established. The Panel recommended that the specifications for E 174 should include the mean particle size and particle size distribution (± SD), as well as the percentage (in number) of particles in the nanoscale (with at least one dimension below 100 nm), present in the powder form of silver (E 174) used as a food additive. The methodology applied should comply with the EFSA Guidance document, e.g. scanning electron microscopy (SEM) or transmission electron microscopy (TEM). The Panel recommended that additional data in line with the current Guidance document on evaluation of food additives would be required.
Editor:
Hoboken: John Wiley & Sons, Inc
Idioma:
Inglês