Idioma:

Clinical Evolution of Laryngeal Granulomas: Treatment and Prognosis

De Lima Pontes, Paulo Augusto ; De Biase, Noemi Grigoletto ; Gadelha, Maria Emília C.

The Laryngoscope, 1999-02, Vol.109 (2), p.289-294 [Periódico revisado por pares]

Hoboken, NJ: John Wiley & Sons, Inc

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Título:
Clinical Evolution of Laryngeal Granulomas: Treatment and Prognosis
Autor: De Lima Pontes, Paulo Augusto ; De Biase, Noemi Grigoletto ; Gadelha, Maria Emília C.
Assuntos: Adolescent ; Adult ; Aged ; Anti-Ulcer Agents - therapeutic use ; Antiemetics - therapeutic use ; Biological and medical sciences ; Botulinum Toxins, Type A - therapeutic use ; Combined Modality Therapy ; Disease Progression ; Domperidone - therapeutic use ; Female ; Gastroesophageal Reflux - complications ; Gastroesophageal Reflux - diagnosis ; Gastroesophageal Reflux - drug therapy ; Granuloma - etiology ; Granuloma - therapy ; Humans ; Laryngeal Diseases - etiology ; Laryngeal Diseases - therapy ; Male ; Medical sciences ; Middle Aged ; Neuromuscular Agents - therapeutic use ; Non tumoral diseases ; Omeprazole - therapeutic use ; Otorhinolaryngology. Stomatology ; Prognosis ; Recurrence ; Retrospective Studies ; Speech Disorders - complications ; Speech Therapy - methods ; Treatment Outcome ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology ; Verbal Behavior
É parte de: The Laryngoscope, 1999-02, Vol.109 (2), p.289-294
Notas: ArticleID:LARY5541090221
istex:31F85197EE4B95177BBCD85FEFBDA357B58EAF53
ark:/67375/WNG-6V9SDL0Z-Z
Descrição: Objective/Hypothesis: To study the response to treatment by patients with granulomas not related to surgery, considering their respective causes. Methods: Retrospective study of larynx granulomas seen at the Institute da Laringe (Sǎo Paulo, Brazil) from June 1996, totaling 66 patients, being 20 (30,3%) diagnosed with gastroesophageal reflux syndrome, 22 (33,3%) due to vocal abuse, 15 (22,7%) to postorotracheal intubation, and 9 (13,6%) of idiopathic cause. Findings: Of the 66 patients diagnosed, 10 did not start the treatment, with only 56 being analyzed, 6 of whom later abandoned the treatment. The cause‐oriented treatment showed 100% control in postintubation granulomas. In the cases of reflux and vocal abuse, the success rates when considering only the cause were 75% and 87.5%, respectively. In the cases of undefined cause, all were subjected to surgical removal with or without clinical or speech‐therapy treatment; we attained only a 37.5% success rate in the first trial. Of these, after various unsuccessful rescue treatments, three which were treated with botulinum toxin type A had 100% resolution. The recurrence percentage varied according to the cause, being nonexistent in the postintubation cases, 21.4% in patients with reflux esophagitis, 35.2% in vocal abuse, and 62.5% in those of idiopathic etiology. Conclusion: Of the laryngeal granulomas, the best prognoses were given by the postintubation ones, whereas the worst were those of undefined cause. Those ascribed to gastroesophageal reflux and vocal abuse have a high resolution rate, although some cases need rescue procedures.
Editor: Hoboken, NJ: John Wiley & Sons, Inc
Idioma: Inglês

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Clinical Evolution of Laryngeal Granulomas: Treatment and Prognosis

De Lima Pontes, Paulo Augusto ; De Biase, Noemi Grigoletto ; Gadelha, Maria Emília C.

Hoboken, NJ: John Wiley & Sons, Inc

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