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18F-FDG PET with or without CT in the diagnosis of extrahepatic metastases or local residual/recurrent hepatocellular carcinoma

Liao, Xiaoli ; Wei, Junbao ; Li, Yongqiang ; Zhong, Jianhong ; Liu, Zhihui ; Liao, Sina ; Li, Qian ; Wei, Changyuan

Medicine (Baltimore), 2018-08, Vol.97 (34), p.e11970-e11970 [Periódico revisado por pares]

United States: Wolters Kluwer Health

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Título:
18F-FDG PET with or without CT in the diagnosis of extrahepatic metastases or local residual/recurrent hepatocellular carcinoma
Autor: Liao, Xiaoli ; Wei, Junbao ; Li, Yongqiang ; Zhong, Jianhong ; Liu, Zhihui ; Liao, Sina ; Li, Qian ; Wei, Changyuan
Assuntos: Adult ; Aged ; Carcinoma, Hepatocellular - diagnostic imaging ; Female ; Fluorodeoxyglucose F18 ; Humans ; Liver Neoplasms - diagnostic imaging ; Male ; Meta-Analysis of Observational Studies in Epidemiology ; Middle Aged ; Neoplasm Metastasis - diagnostic imaging ; Neoplasm Recurrence, Local - diagnostic imaging ; Positron Emission Tomography Computed Tomography - methods ; Positron-Emission Tomography - methods ; Radiopharmaceuticals ; Sensitivity and Specificity
É parte de: Medicine (Baltimore), 2018-08, Vol.97 (34), p.e11970-e11970
Notas: SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ObjectType-Review-1
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Descrição: The aim of the present study was to meta-analyze the literature on the diagnostic value of 18-fluorodeoxyglucose (F-FDG) positron emission tomography (PET) with or without computed tomography (CT) in detecting extrahepatic metastases or local residual/recurrent hepatocellular carcinoma (HCC).Systematic review of literature in MEDLINE, Embase, and Cochrane databases was conducted in March 2017, and relevant studies analyzing the diagnostic performance of F-FDG PET with or without CT were meta-analyzed.Meta-analysis was carried out on data from 11 studies involving 572 patients. F-FDG PET, with or without CT, showed pooled sensitivity of 64% and pooled specificity of 95%. Pooled sensitivity was similar with CT (74%) or without (52%; P = .279). Similarly, pooled specificity was comparable with CT (93%) or without 95% (P = .481).F-FDG PET, with or without CT, shows relatively low sensitivity but high specificity for diagnosing extrahepatic metastases or local residual/recurrent HCC. Adding CT to F-FDG PET may improve diagnostic performance, but the available evidence suggests that the improvement is not statistically significant.
Editor: United States: Wolters Kluwer Health
Idioma: Inglês

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18F-FDG PET with or without CT in the diagnosis of extrahepatic metastases or local residual/recurrent hepatocellular carcinoma

Liao, Xiaoli ; Wei, Junbao ; Li, Yongqiang ; Zhong, Jianhong ; Liu, Zhihui ; Liao, Sina ; Li, Qian ; Wei, Changyuan

United States: Wolters Kluwer Health

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