Idioma:

Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results

Palmini, André ; Gambardella, Antonio ; Andermann, Frederick ; Dubeau, Francois ; da Costa, Jaderson C. ; Olivier, André ; Tampieri, Donatella ; Gloor, Pierre ; Quesney, Felipe ; Andermann, Eva ; Paglioli, Eduardo ; Paglioli-Neto, Eliseu ; Andermann, Ligia Coutinho ; Leblanc, Richard ; Kim, Hyoung-Ihl

Annals of neurology, 1995-04, Vol.37 (4), p.476-487 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

Sem texto completo

Citações Citado por

Enviar para

Título:
Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results
Autor: Palmini, André ; Gambardella, Antonio ; Andermann, Frederick ; Dubeau, Francois ; da Costa, Jaderson C. ; Olivier, André ; Tampieri, Donatella ; Gloor, Pierre ; Quesney, Felipe ; Andermann, Eva ; Paglioli, Eduardo ; Paglioli-Neto, Eliseu ; Andermann, Ligia Coutinho ; Leblanc, Richard ; Kim, Hyoung-Ihl
Assuntos: Adolescent ; Adult ; Biological and medical sciences ; Cerebral Cortex - physiopathology ; Cerebral Cortex - surgery ; Child ; Child, Preschool ; Electroencephalography ; Epilepsies, Partial - physiopathology ; Epilepsies, Partial - surgery ; Female ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Infant ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Treatment Outcome
É parte de: Annals of neurology, 1995-04, Vol.37 (4), p.476-487
Notas: ark:/67375/WNG-B2C7SC9H-2
ArticleID:ANA410370410
istex:04315E1789723C9900094C62C0941D0B9BB5482D
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Cortical dysplastic lesions (CDyLs) are often associated with severe partial epilepsies. We describe the electrographic counterpart of this high degree of epileptogenicity, manifested by continuous or frequent rhythmic epileptogenic discharges recorded directly from CDyLs during intraoperative electrocorticography (ECoG). These ictal or continuous epileptogenic discharges (I/CEDs) assumed one of the following three patterns: (1) repetitive electrographic seizures, (2) repetitive bursting discharges, or (3) continuous or quasicontinuous rhythmic spiking. One or more of these patterns were present in 23 of 34 patients (67%) with intractable partial epilepsy associated with CDyLs, and in only 1 of 40 patients (2.5%) with intractable partial epilepsy associated with other types of structural lesions. I/CEDs were usually spatially restricted, thus contrasting with the more widespread interictal ECoG epileptic activity, and tended to colocalize with the magnetic resonance imaging–defined lesion. Completeness of excision of cortical tissue displaying I/CEDs correlated positively with surgical outcome in patients with medically intractable seizures; i.e., three‐fourths of the patients in whom it was entirely excised had favorble surgical outcome; in contrast, uniformly poor outcome was observed in those patients in whom areas containing I/CEDs remained in situ. We conclude that CDyLs are highly and intrinsically epileptogenic, and that intraoperative ECoG identification of this intrinsically epileptogenic dysplastic cortical tissue is crucial to decide the extent of excision for best seizure control.
Editor: Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

Buscando em bases de dados remotas. Favor aguardar.