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An automated method for the analysis of trabecular bone structure

Aaron, Jean E. ; Johnson, David R. ; Kanis, John A. ; Oakley, Beverley A. ; O'Higgins, Paul ; Paxton, Stephen K.

Computers and biomedical research, 1992-02, Vol.25 (1), p.1-16

SAN DIEGO: Elsevier Inc

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Título:
An automated method for the analysis of trabecular bone structure
Autor: Aaron, Jean E. ; Johnson, David R. ; Kanis, John A. ; Oakley, Beverley A. ; O'Higgins, Paul ; Paxton, Stephen K.
Assuntos: Biological and medical sciences ; Biopsy ; Bone and Bones - anatomy & histology ; Bone and Bones - pathology ; Bone Diseases - pathology ; Bone Matrix - anatomy & histology ; Bone Matrix - pathology ; Computer Science ; Computer Science, Interdisciplinary Applications ; Computerized, statistical medical data processing and models in biomedicine ; Humans ; Image Processing, Computer-Assisted - methods ; Life Sciences & Biomedicine ; Medical Informatics ; Medical management aid. Diagnosis aid ; Medical sciences ; Osteitis Deformans - pathology ; Osteoporosis - pathology ; Science & Technology ; Space life sciences ; Technology
É parte de: Computers and biomedical research, 1992-02, Vol.25 (1), p.1-16
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Trabecular structure as well as bone mass is important in studies of bone disease and fracture. An automated method for the direct analysis of two-dimensional trabecular microanatomy and its application to human iliac crest bone biopsies is described. Compared with established methods which require expensive equipment and complex software, costs have been reduced and availability increased by using an image analyzer driven by a microcomputer. Routine histological sections are accepted and an editing function enables the removal of artifacts. An elastic window allows field expansion for large specimens. The program enables the rapid assessment of the bone volume and trabecular surface from the intact image, followed by image skeletonization and the deduction of the trabecular length, number, character, and spacing together with the number of trabecular junctions and discontinuities; the trabecular width is calculated indirectly. Images may be stored to disk or printed as permanent records for diagnostic or research purposes.
Editor: SAN DIEGO: Elsevier Inc
Idioma: Inglês

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An automated method for the analysis of trabecular bone structure

Aaron, Jean E. ; Johnson, David R. ; Kanis, John A. ; Oakley, Beverley A. ; O'Higgins, Paul ; Paxton, Stephen K.

SAN DIEGO: Elsevier Inc

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