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Aortic Counterpulsation Therapy in Patients with Advanced Heart Failure: Analysis of the TBRIDGE Registry

Bezerra, Cristiano Guedes ; Adam, Eduardo Leal ; Baptista, Mariana Lins ; Ciambelli, Giuliano Serafino ; Kopel, Liliane ; Bernoche, Claudia ; Lopes, Leonardo Nicolau Geisler Daud ; Macatrão-Costa, Milena Frota ; Falcão, Breno de Alencar Araripe ; Lage, Silvia Gelas

Arquivos brasileiros de cardiologia, 2016-01, Vol.106 (1), p.26-32 [Periódico revisado por pares]

Brazil: Sociedade Brasileira de Cardiologia - SBC

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Título:
Aortic Counterpulsation Therapy in Patients with Advanced Heart Failure: Analysis of the TBRIDGE Registry
Autor: Bezerra, Cristiano Guedes ; Adam, Eduardo Leal ; Baptista, Mariana Lins ; Ciambelli, Giuliano Serafino ; Kopel, Liliane ; Bernoche, Claudia ; Lopes, Leonardo Nicolau Geisler Daud ; Macatrão-Costa, Milena Frota ; Falcão, Breno de Alencar Araripe ; Lage, Silvia Gelas
Assuntos: Adult ; Balão Intra-Aórtico ; Brazil ; CARDIAC & CARDIOVASCULAR SYSTEMS ; Cardiomiopatia Chagásica ; Cardiomyopathies - complications ; Cardiomyopathies - mortality ; Chagas Disease - complications ; Chagas Disease - mortality ; Choque Cardiogênico / mortalidade ; Contrapulsação ; Echocardiography ; Female ; Heart Failure - etiology ; Heart Failure - mortality ; Heart Failure - therapy ; Heart Transplantation - adverse effects ; Heart Transplantation - mortality ; Hemodynamics ; Humans ; Insuficiência Cardíaca ; Intra-Aortic Balloon Pumping - methods ; Male ; Middle Aged ; Myocardial Ischemia - complications ; Myocardial Ischemia - mortality ; Original ; Prospective Studies ; Registries - statistics & numerical data ; Risk Factors ; Survival Rate ; Time Factors ; Transplante de Coração ; Treatment Outcome
É parte de: Arquivos brasileiros de cardiologia, 2016-01, Vol.106 (1), p.26-32
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: The use of aortic counterpulsation therapy in advanced heart failure is controversial. To evaluate the hemodynamic and metabolic effects of intra-aortic balloon pump (IABP) and its impact on 30-day mortality in patients with heart failure. Historical prospective, unicentric study to evaluate all patients treated with IABP between August/2008 and July/2013, included in an institutional registry named TBRIDGE (The Brazilian Registry of Intra-aortic balloon pump in Decompensated heart failure - Global Evaluation). We analyzed changes in oxygen central venous saturation (ScvO2), arterial lactate, and use of vasoactive drugs at 48 hours after IABP insertion. The 30-day mortality was estimated by the Kaplan-Meier method and differences in subgroups were evaluated by the Log-rank test. A total of 223 patients (mean age 49 ± 14 years) were included. Mean left ventricle ejection fraction was 24 ± 10%, and 30% of patients had Chagas disease. Compared with pre-IABP insertion, we observed an increase in ScvO2 (50.5% vs. 65.5%, p < 0.001) and use of nitroprusside (33.6% vs. 47.5%, p < 0.001), and a decrease in lactate levels (31.4 vs. 16.7 mg/dL, p < 0.001) and use of vasopressors (36.3% vs. 25.6%, p = 0.003) after IABP insertion. Thirty-day survival was 69%, with lower mortality in Chagas disease patients compared without the disease (p = 0.008). After 48 hours of use, IABP promoted changes in the use of vasoactive drugs, improved tissue perfusion. Chagas etiology was associated with lower 30-day mortality. Aortic counterpulsation therapy is an effective method of circulatory support for patients waiting for heart transplantation.
Editor: Brazil: Sociedade Brasileira de Cardiologia - SBC
Idioma: Inglês;Português

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Aortic Counterpulsation Therapy in Patients with Advanced Heart Failure: Analysis of the TBRIDGE Registry

Bezerra, Cristiano Guedes ; Adam, Eduardo Leal ; Baptista, Mariana Lins ; Ciambelli, Giuliano Serafino ; Kopel, Liliane ; Bernoche, Claudia ; Lopes, Leonardo Nicolau Geisler Daud ; Macatrão-Costa, Milena Frota ; Falcão, Breno de Alencar Araripe ; Lage, Silvia Gelas

Brazil: Sociedade Brasileira de Cardiologia - SBC

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