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RNAi Technology for Insect Management and Protection of Beneficial Insects from Diseases: Lessons, Challenges and Risk Assessments

Zotti, M J ; Smagghe, G

Neotropical entomology, 2015-06, Vol.44 (3), p.197-213 [Periódico revisado por pares]

New York: Springer-Verlag

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Título:
RNAi Technology for Insect Management and Protection of Beneficial Insects from Diseases: Lessons, Challenges and Risk Assessments
Autor: Zotti, M J ; Smagghe, G
Assuntos: adverse effects ; Agriculture ; Animal Diseases - prevention & control ; Animals ; beneficial insects ; Biomedical and Life Sciences ; crops ; disease prevention ; Entomology ; Environment ; Forum ; genes ; human health ; insect control ; Insect Control - methods ; insect pests ; Insecta - genetics ; Life Sciences ; mechanism of action ; MicroRNAs - physiology ; nontarget organisms ; Pest Control, Biological - methods ; risk ; Risk Assessment ; RNA Interference ; RNA, Small Interfering - physiology ; transgenic plants ; Virus Diseases
É parte de: Neotropical entomology, 2015-06, Vol.44 (3), p.197-213
Notas: http://dx.doi.org/10.1007/s13744-015-0291-8
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Descrição: The time has passed for us to wonder whether RNA interference (RNAi) effectively controls pest insects or protects beneficial insects from diseases. The RNAi era in insect science began with studies of gene function and genetics that paved the way for the development of novel and highly specific approaches for the management of pest insects and, more recently, for the treatment and prevention of diseases in beneficial insects. The slight differences in components of RNAi pathways are sufficient to provide a high degree of variation in responsiveness among insects. The current framework to assess the negative effects of genetically modified (GM) plants on human health is adequate for RNAi-based GM plants. Because of the mode of action of RNAi and the lack of genomic data for most exposed non-target organisms, it becomes difficult to determine the environmental risks posed by RNAi-based technologies and the benefits provided for the protection of crops. A better understanding of the mechanisms that determine the variability in the sensitivity of insects would accelerate the worldwide release of commercial RNAi-based approaches.
Editor: New York: Springer-Verlag
Idioma: Inglês;Português

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RNAi Technology for Insect Management and Protection of Beneficial Insects from Diseases: Lessons, Challenges and Risk Assessments

Zotti, M J ; Smagghe, G

New York: Springer-Verlag

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