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O-162 Nested case-control study of skin melanoma incidence in Danish male military pilots

Pedersen, Julie Elbæk ; Hansen, Johnni

Occupational and environmental medicine (London, England), 2023-03, Vol.80 (Suppl 1), p.A12-A13 [Periódico revisado por pares]

London: BMJ Publishing Group Ltd

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  • Título:
    O-162 Nested case-control study of skin melanoma incidence in Danish male military pilots
  • Autor: Pedersen, Julie Elbæk ; Hansen, Johnni
  • Assuntos: Abstracts ; Aircraft pilots ; Confidence intervals ; Employment ; Exposure ; Males ; Melanoma ; Military ; Military personnel ; Occupational exposure ; Occupational health ; Pilots ; Risk ; Skin ; Skin cancer ; Statistical analysis ; Subgroups ; Ultraviolet radiation
  • É parte de: Occupational and environmental medicine (London, England), 2023-03, Vol.80 (Suppl 1), p.A12-A13
  • Notas: Carcinogens/Cancer
    29th International Symposium on Epidemiology in Occupational Health (EPICOH 2023), Mumbai, India, Hosted by the Indian Association of Occupational Health, Mumbai Branch & Tata Memorial Centre
  • Descrição: ObjectivesA positive association between work as a pilot and skin melanoma has been observed in most previous studies, which may be caused by occupational exposure to cosmic and solar ultraviolet A radiation. However, existing evidence is especially limited by lack of information on leisure-time sun habits. The aim of this study was therefore to explore the risk of skin melanoma in pilots, including detailed information on potential confounders.MethodsThis nested case-control study was based on a large nationwide Danish military population comprising 199 male cases with skin melanoma diagnosed between 1990–2003 and 1,126 male cancer-free controls. Data on this population included job history relating to both military service and other jobs as well as socioeconomic and lifestyle characteristics, e.g. sun exposure habits, which had been obtained from a structured questionnaire. Odds ratios (ORs) and corresponding 95% confidence intervals (CI) were estimated by unconditional logistic regression.ResultsAdjusted results indicated a positive association between work onboard aircrafts and skin melanoma (OR=2.30, 95% CI: 1.06–4.97) and the risk seemed only to be elevated in the subgroup of pilots (OR=7.08, 95% CI: 2.51–19.93). Longer duration of employment as pilot was further indicated to increase the risk of skin melanoma (ORper year=1.07, 95% CI: 1.01–1.14).ConclusionsFindings from our study, adjusted for potential confounders, support existing evidence suggesting that pilots have an occupational related increased risk of skin melanoma. However, the association need to be confirmed by future large-scale studies, including detailed objective information on dimensions of exposure and potential confounders.
  • Editor: London: BMJ Publishing Group Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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