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Predictors for new-onset conduction block in patients with pure native aortic regurgitation after transcatheter aortic valve replacement with a new-generation self-expanding valve (VitaFlow Liberty ™ ): a retrospective cohort study

Zhang, Xuan ; Liang, Cheng ; Zha, Lintao ; Zuo, Quan ; Hu, Guobing ; Ding, Jie ; Tang, Shengxing

BMC cardiovascular disorders, 2024-01, Vol.24 (1), p.77-77, Article 77 [Periódico revisado por pares]

England: BioMed Central Ltd

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Predictors for new-onset conduction block in patients with pure native aortic regurgitation after transcatheter aortic valve replacement with a new-generation self-expanding valve (VitaFlow Liberty ™ ): a retrospective cohort study
Autor: Zhang, Xuan ; Liang, Cheng ; Zha, Lintao ; Zuo, Quan ; Hu, Guobing ; Ding, Jie ; Tang, Shengxing
Assuntos: Analysis ; Aorta ; Aortic valve ; Aortic Valve - diagnostic imaging ; Aortic Valve - surgery ; Aortic valve insufficiency ; Aortic Valve Insufficiency - diagnostic imaging ; Aortic Valve Insufficiency - etiology ; Aortic Valve Stenosis - complications ; Aortic Valve Stenosis - diagnostic imaging ; Aortic Valve Stenosis - surgery ; Arrhythmias, Cardiac ; Atrioventricular block ; Atrioventricular Block - diagnosis ; Atrioventricular Block - etiology ; Atrioventricular Block - therapy ; Bundle-Branch Block - diagnosis ; Bundle-Branch Block - etiology ; Bundle-Branch Block - therapy ; Cardiac Pacing, Artificial - adverse effects ; Care and treatment ; Cohort analysis ; Complete left bundle branch block ; Complete right bundle branch block ; Computed tomography ; Coronary vessels ; Diagnosis ; EKG ; Electrocardiogram ; Electrocardiography ; Electronic health records ; Heart ; Heart block ; Heart valve replacement ; Hospitals ; Humans ; Medical imaging ; Medical records ; Morphology ; Mortality ; Pacemaker, Artificial - adverse effects ; Pacemakers ; Patient outcomes ; Permanent pacemaker implantation ; Polyethylene terephthalate ; Pure native aortic regurgitation ; Regression analysis ; Regurgitation ; Retrospective Studies ; Risk Factors ; Transcatheter aortic valve replacement ; Transcatheter Aortic Valve Replacement - adverse effects ; Treatment Outcome ; Ultrasonic imaging ; Ventricle
É parte de: BMC cardiovascular disorders, 2024-01, Vol.24 (1), p.77-77, Article 77
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: New-generation self-expanding valves can improve the success rate of transcatheter aortic valve replacement (TAVR) for severe pure native aortic regurgitation (PNAR). However, predictors of new-onset conduction block post-TAVR using new-generation self-expanding valves in patients with PNAR remain to be established. Therefore, this study aimed to identify predictors of new-onset conduction block post-TAVR using new-generation self-expanding valves (VitaFlow Liberty™) in patients with PNAR. In this retrospective cohort study, patients were categorized into pacemaker and non-pacemaker groups based on their need for new postoperative permanent pacemaker implantation (PPI). Based on the postoperative presence of either new-onset complete left bundle branch block (cLBBB) or high-grade atrioventricular block (AVB), patients were further classified into conduction disorder and non-conduction disorder groups. Laboratory, echocardiographic, computed tomography, preoperative and postoperative electrocardiography, and procedural and clinical data were collected immediately after TAVR and during hospitalization and compared between the groups. Multivariate logistic regression analysis was performed incorporating the significant variables from the univariate analyses. This study examined 68 consecutive patients with severe PNAR who underwent TAVR. In 20 patients, a permanent pacemaker was fitted postoperatively. Multivariate logistic regression analysis revealed an association between the need for postoperative PPI and preoperative complete right bundle branch block (cRBBB) or first-degree AVB, as well as a non-tubular left ventricular outflow tract (LVOT). In addition, valve implantation depth and angle of aortic root were independent predictors of new-onset cLBBB or high-grade AVB developing post-TAVR. The predictive value of valve implantation depth and angle of aortic root was further supported by receiver operating characteristic curve analysis results. In patients with PNAR undergoing TAVR using self-expanding valves, preoperative cRBBB or first-degree AVB and a non-tubular LVOT were indicators of a higher likelihood of PPI requirement. Moreover, deeper valve implantation depth and greater angle of aortic root may be independent risk factors for new-onset cLBBB or high-grade AVB post-TAVR. Valve implantation depth and angle of aortic root values may be used to predict the possibility of new cLBBB or high-grade AVB post-TAVR.
Editor: England: BioMed Central Ltd
Idioma: Inglês

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Predictors for new-onset conduction block in patients with pure native aortic regurgitation after transcatheter aortic valve replacement with a new-generation self-expanding valve (VitaFlow Liberty ™ ): a retrospective cohort study

Zhang, Xuan ; Liang, Cheng ; Zha, Lintao ; Zuo, Quan ; Hu, Guobing ; Ding, Jie ; Tang, Shengxing

England: BioMed Central Ltd

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