Idioma:

Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas

Friedman, Gregory K ; Johnston, James M ; Bag, Asim K ; Bernstock, Joshua D ; Li, Rong ; Aban, Inmaculada ; Kachurak, Kara ; Nan, Li ; Kang, Kyung-Don ; Totsch, Stacie ; Schlappi, Charles ; Martin, Allison M ; Pastakia, Devang ; McNall-Knapp, Rene ; Farouk Sait, Sameer ; Khakoo, Yasmin ; Karajannis, Matthias A ; Woodling, Karina ; Palmer, Joshua D ; Osorio, Diana S ; Leonard, Jeffrey ; Abdelbaki, Mohamed S ; Madan-Swain, Avi ; Atkinson, T. Prescott ; Whitley, Richard J ; Fiveash, John B ; Markert, James M ; Gillespie, G. Yancey

The New England journal of medicine, 2021-04, Vol.384 (17), p.1613-1622 [Periódico revisado por pares]

United States: Massachusetts Medical Society

Texto completo disponível

Citações Citado por

Enviar para

Título:
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
Autor: Friedman, Gregory K ; Johnston, James M ; Bag, Asim K ; Bernstock, Joshua D ; Li, Rong ; Aban, Inmaculada ; Kachurak, Kara ; Nan, Li ; Kang, Kyung-Don ; Totsch, Stacie ; Schlappi, Charles ; Martin, Allison M ; Pastakia, Devang ; McNall-Knapp, Rene ; Farouk Sait, Sameer ; Khakoo, Yasmin ; Karajannis, Matthias A ; Woodling, Karina ; Palmer, Joshua D ; Osorio, Diana S ; Leonard, Jeffrey ; Abdelbaki, Mohamed S ; Madan-Swain, Avi ; Atkinson, T. Prescott ; Whitley, Richard J ; Fiveash, John B ; Markert, James M ; Gillespie, G. Yancey
Assuntos: Adolescent ; Adolescents ; Adverse events ; Biopsy ; Brain cancer ; Brain Neoplasms - diagnostic imaging ; Brain Neoplasms - pathology ; Brain Neoplasms - radiotherapy ; Brain Neoplasms - therapy ; Brain tumors ; Catheters ; Chemotherapy ; Child ; Child, Preschool ; Children ; Clinical trials ; Combined Modality Therapy ; Conjunctiva ; Drug dosages ; Drug therapy ; Female ; Genetic engineering ; Glioma ; Glioma - diagnostic imaging ; Glioma - pathology ; Glioma - radiotherapy ; Glioma - therapy ; Gliomas ; Herpes simplex ; Herpes simplex virus ; Herpes viruses ; Humans ; Immunotherapy ; Kaplan-Meier Estimate ; Killer Cells, Natural ; Kinases ; Leukocyte Count ; Lymphocytes ; Male ; Oncolysis ; Oncolytic Virotherapy - adverse effects ; Patient outcomes ; Patients ; Pediatrics ; Polymerase chain reaction ; Saliva ; T-Lymphocytes ; Teenagers ; Testing ; Tumor-infiltrating lymphocytes ; Tumors
É parte de: The New England journal of medicine, 2021-04, Vol.384 (17), p.1613-1622
Descrição: A neurotropic herpes simplex virus that was genetically inactivated to prevent replication in normal cells was injected into the brain tumors of 12 patients with tumors that had progressed during previous treatment. Eleven patients had some radiographic or clinical responses, with inflammation detected in some PET scans. The median survival was 12.2 months, and 4 of 11 patients were still alive 18 months after treatment.
Editor: United States: Massachusetts Medical Society
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 3 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas

United States: Massachusetts Medical Society

Buscando em bases de dados remotas. Favor aguardar.