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Overview of latest clinical advances

Francesca Cordeiro, M.

Acta ophthalmologica (Oxford, England), 2019-12, Vol.97 (S263), p.n/a [Periódico revisado por pares]

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Título:
Overview of latest clinical advances
Autor: Francesca Cordeiro, M.
Assuntos: Clinical trials ; Glaucoma ; Medical treatment ; Memantine ; Movement disorders ; Neurodegeneration ; Neurodegenerative diseases ; Neuroprotection ; Ophthalmology ; Parkinson's disease
É parte de: Acta ophthalmologica (Oxford, England), 2019-12, Vol.97 (S263), p.n/a
Descrição: The realisation that lowering IOP is unable to prevent progressive vision loss in all glaucoma patients, has led to investigation of neuroprotection as an alternative or additional treatment option. Although confirmation of neuroprotective effects by randomized clinical trials is needed, there was a demonstration of positive non‐IOP dependent effects in the LoGTS study, although recently negative published results of the Memantine study. Furthermore, it has been proposed as a treatment strategy in other ocular diseases, such as AMD. Neuroprotection has been advocated for many years in neurodegeneration. Indeed, the therapies that have been suggested in Alzheimer’s and Parkinson’s Disease are similar to those investigated in ophthalmology. This talk will review the evidence for neuroprotection and its role in glaucoma and application as a practical and future treatment strategy.
Editor: Malden: Wiley Subscription Services, Inc
Idioma: Inglês

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