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血液透析和腹膜透析对终末期肾脏病患者钙磷代谢影响研究

陈霞;王俊霞;郭琼琼;马宛宛;宁小元

中国全科医学, 2017, Vol.20 (2), p.1-5 [Periódico revisado por pares]

471003 河南省洛阳市,河南科技大学临床医学院,河南科技大学第一附属医院

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  • Título:
    血液透析和腹膜透析对终末期肾脏病患者钙磷代谢影响研究
  • Autor: 陈霞; 王俊霞; 郭琼琼; 马宛宛; 宁小元
  • Assuntos: 影响因素 ; 肾病 ; 腹膜透析 ; 血液透析 ; 钙磷代谢
  • É parte de: 中国全科医学, 2017, Vol.20 (2), p.1-5
  • Notas: CHEN Xia;WANG Jun-xia;GUO Qiong-qiong;The First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology
    Objective To study the influence of hemodialysis（ HD） and peritoneal dialysis（ PD） on calcium and phosphorus metabolism disorders in patients with end stage renal disease（ ESRD） in order to provide the clinical basis for the improvement of calcium and phosphorus metabolism disorders. Methods HD patients 276 cases（ as HD group） and 236 cases of PD patients（ as group PD） in the First Affiliated Hospital of Henan University of Science and Technology from 2012 to 2015,then all the patients with hemodialysis were divided into 5 groups, 〈 3-12 month group, 〈 12-24 month group, 〈 24-36 month group, 〈 36-48 month group, 〈 48 month group. The serum calcium and phosphorus,parathyroid hormone,calcium phosphorus product in hemodialysis patients were analyzed. The influencing factors of calcium and phosphorus metabolism disorders in patients with HD and PD were analyzed. Results
  • Descrição: 目的探讨血液透析（HD）和腹膜透析（PD）对终末期肾脏病（ESRD）患者钙磷代谢的影响,为改善ESRD患者钙磷代谢紊乱提供临床依据。方法选取2012—2015年河南科技大学第一附属医院收治的HD患者276例（作为HD组）和PD患者236例（作为PD组）,再将所有患者按透析龄分为5组,〈312个月组、〈1224个月组、〈2436个月组、〈3648个月组、〈48个月组。分析各透析龄组患者血钙、血磷、全段甲状旁腺素、钙磷乘积,并分析HD、PD患者钙磷代谢紊乱的影响因素。结果 〈2436个月组、〈3648个月组、〈48个月组HD、PD患者血钙、血磷、甲状旁腺素比较,差异有统计学意义（P〈0.05）;〈3648个月组、〉48个月组HD、PD患者钙磷乘积比较,差异有统计学意义（P〈0.05）。年龄、透析龄、血红蛋白、三酰甘油、β2微球蛋白、尿素清除指数（Kt/V）是PD患者钙磷代谢紊乱的影响因素（P〈0.05）;年龄、透析龄、β2微球蛋白、Kt/V是HD患者钙磷代谢紊乱的影响因素（P〈0.05）。结论 ESRD患者钙磷代谢紊乱普遍存在,与HD相比,PD患者钙磷代谢紊乱发生率相对低。提高透析充分性可改善血透和腹透患者钙磷代谢紊乱,积极改善贫血,降脂等加强一体化治疗有助于纠正HD患者钙磷代谢紊乱。
  • Editor: 471003 河南省洛阳市,河南科技大学临床医学院,河南科技大学第一附属医院
  • Idioma: Chinês
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