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Fractionated radiotherapy and radiosurgery of intracranial meningiomas

Biau, J ; Khalil, T ; Verrelle, P ; Lemaire, J.-J

Neuro-chirurgie, 2018-03, Vol.64 (1), p.29-36 [Periódico revisado por pares]

France: Elsevier Masson SAS

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  • Título:
    Fractionated radiotherapy and radiosurgery of intracranial meningiomas
  • Autor: Biau, J ; Khalil, T ; Verrelle, P ; Lemaire, J.-J
  • Assuntos: Bioengineering ; Cognitive science ; Computer Science ; Engineering Sciences ; Human health and pathology ; Imaging ; Life Sciences ; Medical Imaging ; Meningioma ; Méningiome ; Neurobiology ; Neurons and Cognition ; Neuroscience ; Neurosurgery ; Radiochirurgie ; Radiosurgery ; Radiotherapy ; Radiothérapie ; Signal and Image processing ; Surgery
  • É parte de: Neuro-chirurgie, 2018-03, Vol.64 (1), p.29-36
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: Abstract This review focuses on the role of radiosurgery and fractionated radiotherapy in the management of intracranial meningiomas, which are the most common benign intracranial tumors. Whenever feasible, surgery remains a cornerstone of treatment in effective health care treatment where modern radiotherapy plays an important role. Irradiation can be proposed as first-line treatment, as adjuvant treatment, or as a second-line treatment after recurrence. Stereotactic radiosurgery consists of delivering, a high-dose of radiation with high precision, to the tumor in a single-fraction with a minimal exposure of surrounding healthy tissue. Stereotactic radiosurgery, especially with the gamma knife technique, has reached a high level of success for the treatment of intracranial meningiomas with excellent local control and low morbidity. However, stereotactic radiosurgery is limited by tumor size, < 3–4 cm, and location, i.e. reasonable distance from the organs at risk. Fractionated radiation therapy is an interesting alternative (5 to 6 weeks treatment time) for large inoperable tumors. The results of fractionated radiation therapy seem encouraging as regards both local control and morbidity although long-term prospective studies are still needed.
  • Editor: France: Elsevier Masson SAS
  • Idioma: Inglês
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