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Association Between a Low Ankle-Brachial Index and Dementia in a General Elderly Population in Central Africa (Epidemiology of Dementia in Central Africa Study)

Guerchet, Maëlenn ; Mbelesso, Pascal ; Mouanga, Alain M. ; Tabo, André ; Bandzouzi, Bébène ; Clément, Jean-Pierre ; Lacroix, Philippe ; Preux, Pierre-Marie ; Aboyans, Victor

Journal of the American Geriatrics Society (JAGS), 2013-07, Vol.61 (7), p.1135-1140 [Periódico revisado por pares]

Hoboken, NJ: Blackwell Publishing Ltd

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Título:
Association Between a Low Ankle-Brachial Index and Dementia in a General Elderly Population in Central Africa (Epidemiology of Dementia in Central Africa Study)
Autor: Guerchet, Maëlenn ; Mbelesso, Pascal ; Mouanga, Alain M. ; Tabo, André ; Bandzouzi, Bébène ; Clément, Jean-Pierre ; Lacroix, Philippe ; Preux, Pierre-Marie ; Aboyans, Victor
Assuntos: Africa ; Aged ; Ankle Brachial Index ; Atherosclerosis ; Biological and medical sciences ; Cardiovascular disease ; Central African Republic ; Central African Republic - epidemiology ; Chi-Square Distribution ; Congo ; Congo - epidemiology ; Cross-Sectional Studies ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Dementia ; Dementia - epidemiology ; Epidemiology ; Female ; General aspects ; Geriatrics ; Humans ; Life Sciences ; Logistic Models ; Male ; Medical sciences ; Neurology ; Neuropsychological Tests ; peripheral arterial disease ; Peripheral Vascular Diseases ; Peripheral Vascular Diseases - epidemiology ; Prevalence ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Santé publique et épidémiologie
É parte de: Journal of the American Geriatrics Society (JAGS), 2013-07, Vol.61 (7), p.1135-1140
Notas: istex:BCF3A91A9E18A219CE9D53433A59120565E51460
ArticleID:JGS12310
ark:/67375/WNG-5H9299TR-0
French Ministry of Foreign Affairs as part of the Coopération pour la Recherche Universitaire et Scientifique programme - No. 6024-4
ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: Objectives To investigate the association between peripheral arterial disease (PAD) and dementia in native elderly African populations. Design Two successive door‐to‐door cross‐sectional surveys in the general population. Settings Representative districts of Bangui (Central African Republic) and Brazzaville (Republic of Congo). Participants Population aged 65 and older. Measurements Peripheral arterial disease was defined as an ankle–brachial index (ABI) of 0.90 or less. Cognitive screening was performed using the Community Screening Interview for Dementia and the Five‐Word Test. Diagnosis of dementia was confirmed after further neuropsychological tests and neurological examination according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria. Multivariate logistic regression models were used to quantify the association between PAD and dementia in those populations, with adjustments for cardiovascular disease (CVD) and other variables. Results A significant association was observed between PAD and prevalent dementia (odds ratio (OR) = 2.43, 95% confidence interval (CI) = 1.44–4.13, P = .001), even after adjustment for age, city, sex, CVD risk factors, education, and depressive disorders (OR = 2.37, 95% CI = 1.31–4.26, P = .004). This association was stronger with lower ABI. Conclusion These findings support the hypothesis of a link between atherosclerosis (represented by a low ABI) and cognitive disorders in native Africans and are similar to previous reports in African Americans and other ethnic groups.
Editor: Hoboken, NJ: Blackwell Publishing Ltd
Idioma: Inglês

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Association Between a Low Ankle-Brachial Index and Dementia in a General Elderly Population in Central Africa (Epidemiology of Dementia in Central Africa Study)

Guerchet, Maëlenn ; Mbelesso, Pascal ; Mouanga, Alain M. ; Tabo, André ; Bandzouzi, Bébène ; Clément, Jean-Pierre ; Lacroix, Philippe ; Preux, Pierre-Marie ; Aboyans, Victor

Hoboken, NJ: Blackwell Publishing Ltd

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