skip to main content
Guest
e-Shelf
My Account
Sign out
Sign in
This feature requires javascript
Tags
e-Journals
e-Books
Databases
USP Libraries
Help
Help
Language:
English
Spanish
Portuguese (Brazil)
This feature required javascript
This feature requires javascript
Primo Search
General Search
General Search
Physical Collection
Physical Collections
USP Intelectual Production
USP Production
Search For:
Clear Search Box
Search in:
General Search
Or hit Enter to replace search target
Or select another collection:
Search in:
General Search
Advanced Search
Browse Search
This feature requires javascript
This feature requires javascript
Neurophysiopathological Aspects of Paclitaxel-induced Peripheral Neuropathy
Velasco-González, Roberto ; Coffeen, Ulises
Neurotoxicity research, 2022-12, Vol.40 (6), p.1673-1689
[Peer Reviewed Journal]
New York: Springer US
Full text available
Citations
Cited by
View Online
Details
Reviews & Tags
More
Times Cited
This feature requires javascript
Actions
Add to e-Shelf
Remove from e-Shelf
E-mail
Print
Permalink
Citation
EasyBib
EndNote
RefWorks
Delicious
Export RIS
Export BibTeX
This feature requires javascript
Title:
Neurophysiopathological Aspects of Paclitaxel-induced Peripheral Neuropathy
Author:
Velasco-González, Roberto
;
Coffeen, Ulises
Subjects:
Antineoplastic Agents - adverse effects
;
Biomedical and Life Sciences
;
Biomedicine
;
Cell Biology
;
Docetaxel
;
Humans
;
Microtubules - metabolism
;
Neuralgia - chemically induced
;
Neuralgia - metabolism
;
Neurobiology
;
Neurochemistry
;
Neurology
;
Neurosciences
;
Oxidative Stress
;
Paclitaxel - toxicity
;
Pharmacology/Toxicology
;
Review Article
Is Part Of:
Neurotoxicity research, 2022-12, Vol.40 (6), p.1673-1689
Description:
Chemotherapy is widely used as a primary treatment or adjuvant therapy for cancer. Anti-microtubule agents (such as paclitaxel and docetaxel) are used for treating many types of cancer, either alone or in combination. However, their use has negative consequences that restrict the treatment's ability to continue. The principal negative effect is the so-called chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a complex ailment that depends on diversity in the mechanisms of action of the different chemotherapy drugs, which are not fully understood. In this paper, we review several neurophysiological and pathological characteristics, such as morphological changes, changes in ion channels, mitochondria and oxidative stress, cell death, changes in the immune response, and synaptic control, as well as the characteristics of neuropathic pain produced by paclitaxel.
Publisher:
New York: Springer US
Language:
English
Links
View this record in MEDLINE/PubMed
This feature requires javascript
This feature requires javascript
Back to results list
Previous
Result
13
Next
This feature requires javascript
This feature requires javascript
Searching Remote Databases, Please Wait
Searching for
in
scope:(USP_VIDEOS),scope:("PRIMO"),scope:(USP_FISICO),scope:(USP_EREVISTAS),scope:(USP),scope:(USP_EBOOKS),scope:(USP_PRODUCAO),primo_central_multiple_fe
Show me what you have so far
This feature requires javascript
This feature requires javascript