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MOESM1 of Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

Bodart-Santos, Victor ; Carvalho, Luiza ; Godoy, Mariana ; Batista, André ; Saraiva, Leonardo ; Lima, Luize ; Abreu, Carla ; Felice, Fernanda ; Galina, Antonio ; Mendez-Otero, Rosalia ; Ferreira, Sergio

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MOESM1 of Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers
Autor: Bodart-Santos, Victor ; Carvalho, Luiza ; Godoy, Mariana ; Batista, André ; Saraiva, Leonardo ; Lima, Luize ; Abreu, Carla ; Felice, Fernanda ; Galina, Antonio ; Mendez-Otero, Rosalia ; Ferreira, Sergio
Assuntos: Biochemistry ; Biophysics ; Biotechnology ; Cell Biology ; Developmental Biology ; FOS: Biological sciences ; Genetics ; Neuroscience ; Physiology ; Space Science
Notas: RelationTypeNote: IsSupplementTo -- 10.1186/s13287-019-1432-5
10.1186/s13287-019-1432-5
Descrição: Additional file 1: Figure S1. Characterization of human Wharton’s Jelly mesenchymal stem cells (hMSCs). a MSCs had fibroblast-like morphology and stemness was confirmed by adipogenic (b, Oil Red O labeling) or chondrogenic differentiation (c, Alcian blue labeling). Scale bars, 50 μm. MSC phenotype was further confirmed by flow cytometry. Cells maintained in control medium (d) or serum-free medium (e) for 24 h were immunolabeled with antibodies against HLA-DR, CD14, CD34, CD45, CD73, CD90, CD105 or CD146. Green traces correspond to fluorescence intensities of markers, while purple shaded curves indicate isotypic controls.
Editor: figshare
Data de criação/publicação: 2019
Idioma: Inglês

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