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The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: Two years' follow-up of the randomized controlled trial

Kemler, Marius A. ; De Vet, Henrica C. W. ; Barendse, Gerard A. M. ; Van Den Wildenberg, Frans A. J. M. ; Van Kleef, Maarten

Annals of neurology, 2004-01, Vol.55 (1), p.13-18 [Peer Reviewed Journal]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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Title:
The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: Two years' follow-up of the randomized controlled trial
Author: Kemler, Marius A. ; De Vet, Henrica C. W. ; Barendse, Gerard A. M. ; Van Den Wildenberg, Frans A. J. M. ; Van Kleef, Maarten
Subjects: Adolescent ; Adult ; Aged ; Biological and medical sciences ; Chronic Disease - therapy ; Electric Stimulation Therapy - methods ; Follow-Up Studies ; Humans ; Medical sciences ; Middle Aged ; Neurology ; Pain Management ; Physical Therapy Modalities ; Prospective Studies ; Quality of Life ; Recovery of Function ; Reflex Sympathetic Dystrophy - therapy ; Spinal Cord - physiology ; Treatment Outcome
Is Part Of: Annals of neurology, 2004-01, Vol.55 (1), p.13-18
Notes: istex:82B24611A75C1549EE3B0CE30B2F98C649BEF9ED
ark:/67375/WNG-5TR9P8N9-1
Dutch Health Insurance Council - No. OG 96-006
ArticleID:ANA10996
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
Description: Chronic reflex sympathetic dystrophy is a painful, disabling disorder for which no treatment with proven effect is available. We performed a randomized trial in a 2 to 1 ratio of patients, in which 36 patients were treated with spinal cord stimulation and physical therapy (SCS+PT), and 18 patients received solely PT. Twenty‐four SCS+PT patients were given a permanent spinal cord stimulation system after successful test stimulation; the remaining 12 patients received no permanent system. We assessed pain intensity, global perceived effect, functional status, and health‐related quality of life. Patients were examined before randomization, before implantation, and also at 1, 3, 6, 12, and 24 months thereafter. At 2 years, three patients were excluded from the analysis. The intention‐to‐treat analysis showed improvements in the SCS+PT group concerning pain intensity (−2.1 vs 0.0cm; p < 0.001) and global perceived effect (43% vs 6% “much improved”; p = 0.001). There was no clinically important improvement of functional status. Health‐related quality of life improved only in the group receiving spinal cord stimulation. After careful selection and successful test stimulation, spinal cord stimulation results in a long‐term pain reduction and health‐related quality of life improvement in chronic reflex sympathetic dystrophy.
Publisher: Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Language: English

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The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: Two years' follow-up of the randomized controlled trial

Kemler, Marius A. ; De Vet, Henrica C. W. ; Barendse, Gerard A. M. ; Van Den Wildenberg, Frans A. J. M. ; Van Kleef, Maarten

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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