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Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers

McCullough, Marjorie L ; Weinstein, Stephanie J ; Freedman, D Michal ; Helzlsouer, Kathy ; Flanders, W Dana ; Koenig, Karen ; Kolonel, Laurence ; Laden, Francine ; Le Marchand, Loic ; Purdue, Mark ; Snyder, Kirk ; Stevens, Victoria L ; Stolzenberg-Solomon, Rachael ; Virtamo, Jarmo ; Yang, Gong ; Yu, Kai ; Zheng, Wei ; Albanes, Demetrius ; Ashby, Jason ; Bertrand, Kimberly ; Cai, Hui ; Chen, Yu ; Gallicchio, Lisa ; Giovannucci, Edward ; Jacobs, Eric J ; Hankinson, Susan E ; Hartge, Patricia ; Hartmuller, Virginia ; Harvey, Chinonye ; Hayes, Richard B ; Horst, Ronald L ; Shu, Xiao-Ou

American journal of epidemiology, 2010-07, Vol.172 (1), p.21-35 [Periódico revisado por pares]

United States: Oxford Publishing Limited (England)

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Título:
Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
Autor: McCullough, Marjorie L ; Weinstein, Stephanie J ; Freedman, D Michal ; Helzlsouer, Kathy ; Flanders, W Dana ; Koenig, Karen ; Kolonel, Laurence ; Laden, Francine ; Le Marchand, Loic ; Purdue, Mark ; Snyder, Kirk ; Stevens, Victoria L ; Stolzenberg-Solomon, Rachael ; Virtamo, Jarmo ; Yang, Gong ; Yu, Kai ; Zheng, Wei ; Albanes, Demetrius ; Ashby, Jason ; Bertrand, Kimberly ; Cai, Hui ; Chen, Yu ; Gallicchio, Lisa ; Giovannucci, Edward ; Jacobs, Eric J ; Hankinson, Susan E ; Hartge, Patricia ; Hartmuller, Virginia ; Harvey, Chinonye ; Hayes, Richard B ; Horst, Ronald L ; Shu, Xiao-Ou
Assuntos: Adult ; Analysis of Variance ; Body mass index ; Case-Control Studies ; China - epidemiology ; Cohort Studies ; Diet ; Endometrial Neoplasms - epidemiology ; Endometrial Neoplasms - ethnology ; Endometrial Neoplasms - prevention & control ; Esophageal Neoplasms - epidemiology ; Esophageal Neoplasms - ethnology ; Esophageal Neoplasms - prevention & control ; Female ; Finland - epidemiology ; Humans ; Kidney Neoplasms - epidemiology ; Kidney Neoplasms - ethnology ; Kidney Neoplasms - prevention & control ; Logistic Models ; Lymphoma, Non-Hodgkin - epidemiology ; Lymphoma, Non-Hodgkin - ethnology ; Lymphoma, Non-Hodgkin - prevention & control ; Male ; Minority & ethnic groups ; Neoplasms - ethnology ; Neoplasms - prevention & control ; Original Contributions ; Ovarian Neoplasms - epidemiology ; Ovarian Neoplasms - ethnology ; Ovarian Neoplasms - prevention & control ; Pancreatic Neoplasms - epidemiology ; Pancreatic Neoplasms - ethnology ; Pancreatic Neoplasms - prevention & control ; Prospective Studies ; Risk Factors ; Stomach Neoplasms - epidemiology ; Stomach Neoplasms - ethnology ; Stomach Neoplasms - prevention & control ; United States - epidemiology ; Vitamin D ; Vitamin D - blood ; Vitamin D - therapeutic use ; Vitamin D Deficiency - complications ; Vitamin D Deficiency - epidemiology ; Vitamin D Deficiency - ethnology ; Vitamin D Deficiency - prevention & control ; Vitamin deficiency
É parte de: American journal of epidemiology, 2010-07, Vol.172 (1), p.21-35
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: Low vitamin D status is common globally and is associated with multiple disease outcomes. Understanding the correlates of vitamin D status will help guide clinical practice, research, and interpretation of studies. Correlates of circulating 25-hydroxyvitamin D (25(OH)D) concentrations measured in a single laboratory were examined in 4,723 cancer-free men and women from 10 cohorts participating in the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers, which covers a worldwide geographic area. Demographic and lifestyle characteristics were examined in relation to 25(OH)D using stepwise linear regression and polytomous logistic regression. The prevalence of 25(OH)D concentrations less than 25 nmol/L ranged from 3% to 36% across cohorts, and the prevalence of 25(OH)D concentrations less than 50 nmol/L ranged from 29% to 82%. Seasonal differences in circulating 25(OH)D were most marked among whites from northern latitudes. Statistically significant positive correlates of 25(OH)D included male sex, summer blood draw, vigorous physical activity, vitamin D intake, fish intake, multivitamin use, and calcium supplement use. Significant inverse correlates were body mass index, winter and spring blood draw, history of diabetes, sedentary behavior, smoking, and black race/ethnicity. Correlates varied somewhat within season, race/ethnicity, and sex. These findings help identify persons at risk for low vitamin D status for both clinical and research purposes.
Editor: United States: Oxford Publishing Limited (England)
Idioma: Inglês

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Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers

United States: Oxford Publishing Limited (England)

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