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Cavernous sinus metastasis in head and neck cancer: Focus on oral squamous cell cancer

Segna, E. ; Civita, F. ; Denaro, N. ; Beltramini, G.A.

Oral oncology, 2024-05, Vol.152, p.106784-106784, Article 106784 [Periódico revisado por pares]

England: Elsevier Ltd

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Cavernous sinus metastasis in head and neck cancer: Focus on oral squamous cell cancer
Autor: Segna, E. ; Civita, F. ; Denaro, N. ; Beltramini, G.A.
Assuntos: Adult ; Aged ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - secondary ; Cavernous sinus ; Cavernous Sinus - diagnostic imaging ; Cavernous Sinus - pathology ; Female ; Head and neck cancer ; Head and Neck Neoplasms - pathology ; Humans ; Immunotherapy ; Male ; Metastasis ; Middle Aged ; Mouth Neoplasms - pathology ; Mouth Neoplasms - therapy ; Neurologic manifestations ; Ophtalmoplegia ; Oral cancer
É parte de: Oral oncology, 2024-05, Vol.152, p.106784-106784, Article 106784
Notas: SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
Descrição: Intracranial metastatic disease is rarely found in head and neck cancer (HNC), in particular, cavernous sinus (CS) involvement is difficult to recognize, because of its rarity, not specific symptoms associated and challenging imaging features. We report our experience in 4 cases, reviewing also the English literature. We analysed data from 21 patients showing that CS metastasis is a dramatic event, with rapid onset, usually starting with neurological manifestations (ophthalmoplegia, headache and trigeminal dysesthesia) and almost unavoidable outcome (DOD in 18/21 patients). Furthermore, we assessed that the diagnostic confirmation could be difficult to perform because of the need for multiple exams and time consuming procedures. Unfortunately, usual antineoplastic therapies seem to be not effective in prolonging survival, also because patients are already weakened by primary tumour treatments. The only option that seems useful in improving outcomes is immunotherapy.
Editor: England: Elsevier Ltd
Idioma: Inglês

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Cavernous sinus metastasis in head and neck cancer: Focus on oral squamous cell cancer

Segna, E. ; Civita, F. ; Denaro, N. ; Beltramini, G.A.

England: Elsevier Ltd

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