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Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazon

de Freitas, Vera Lúcia Teixeira ; Esper, Helena Rangel ; Nakanishi, Erika Shimoda ; Piotto, Mariana Ramos ; Assy, João Guilherme Pontes Lima ; Berreta, Olívia Campos Pinheiro ; Said, Renato do Carmo ; Segurado, Aluisio Augusto Cotrim ; Carvalho, Noemia Barbosa ; França, Francisco Oscar de Siqueira ; Lopes, Marta Heloísa

Revista do Instituto de Medicina Tropical de São Paulo, 2021-01, Vol.63, p.1-5 [Periódico revisado por pares]

São Paulo: Instituto de Medicina Tropical de Sao Paulo

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Título:
Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazon
Autor: de Freitas, Vera Lúcia Teixeira ; Esper, Helena Rangel ; Nakanishi, Erika Shimoda ; Piotto, Mariana Ramos ; Assy, João Guilherme Pontes Lima ; Berreta, Olívia Campos Pinheiro ; Said, Renato do Carmo ; Segurado, Aluisio Augusto Cotrim ; Carvalho, Noemia Barbosa ; França, Francisco Oscar de Siqueira ; Lopes, Marta Heloísa
Assuntos: Acute Chagas disease ; Asymptomatic ; Breastfeeding & lactation ; Case Report ; Chagas disease ; Child ; Congenital diseases ; Diagnosis ; DTUs ; Electrocardiography ; Epidemics ; Hospitals ; Infections ; Microscopy ; Oral outbreak ; Protozoa ; Serology ; TROPICAL MEDICINE ; Trypanosoma cruzi ; Vertical transmission
É parte de: Revista do Instituto de Medicina Tropical de São Paulo, 2021-01, Vol.63, p.1-5
Notas: CONFLICT OF INTERESTS
VLTF and HRE conceptualized and designed the study; JGPLA, OCPB, RCS, NBC, designed the data collection instruments, collected data, carried out the initial analyses; EYSN and MRP, carried out the molecular assays and the initial analyses; AACS, FOSF, and MHL coordinated and supervised data collection, have written and critically reviewed the manuscript. All authors reviewed and approved the final manuscript as submitted and agreed to be accountable for all aspects of the study.
The authors have no conflict of interests to disclose.
AUTHORS’ CONTRIBUTIONS
Descrição: This study describes difficulties in the monitoring of a child born during an oral outbreak of Chagas disease, in which there are several indications that the transmission occurred through the congenital route: 1. the mother was in the third trimester of pregnancy when she was infected; 2. She presented high parasitemia at the time of delivery; 3. In both, the mother and her daughter, T. cruzi was classified as DTU TcIV. The parasites were not found in the blood at birth and the infection was detected only three months later in an asymptomatic infant. As the mother and her child live in a highly endemic area, vector transmission could not be excluded during this period.
Editor: São Paulo: Instituto de Medicina Tropical de Sao Paulo
Idioma: Inglês;Português

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Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazon

São Paulo: Instituto de Medicina Tropical de Sao Paulo

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