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ATP excites mouse vomeronasal sensory neurons through activation of P2X receptors

Vick, J.S ; Delay, R.J

Neuroscience, 2012-09, Vol.220, p.341-350 [Periódico revisado por pares]

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Título:
ATP excites mouse vomeronasal sensory neurons through activation of P2X receptors
Autor: Vick, J.S ; Delay, R.J
Assuntos: adenosine 5′-triphosphate ; Adenosine Triphosphate - metabolism ; Animals ; Biological and medical sciences ; excitability ; Female ; Fundamental and applied biological sciences. Psychology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neurology ; Neurons - metabolism ; Patch-Clamp Techniques ; perforated patch clamp ; pheromones ; purinergic receptors ; Receptors, Purinergic P2X - metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Sensory Receptor Cells - metabolism ; Vertebrates: nervous system and sense organs ; vomeronasal organ
É parte de: Neuroscience, 2012-09, Vol.220, p.341-350
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Highlights ► Purinergic signaling is an important component of the chemical senses. ► ATP increased intracellular calcium in VSNs through P2X receptors. ► ATP elicited an inward current and action potentials in VSNs through P2X receptors. ► The chemosensory response of VSNs was increased by ATP. ► Mechanical stimulation of the VNO induced ATP release.
Editor: Amsterdam: Elsevier Ltd
Idioma: Inglês

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