Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Lombardo, Louis J ; Lee, Francis Y ; Chen, Ping ; Norris, Derek ; Barrish, Joel C ; Behnia, Kamelia ; Castaneda, Stephen ; Cornelius, Lyndon A. M ; Das, Jagabandhu ; Doweyko, Arthur M ; Fairchild, Craig ; Hunt, John T ; Inigo, Ivan ; Johnston, Kathy ; Kamath, Amrita ; Kan, David ; Klei, Herbert ; Marathe, Punit ; Pang, Suhong ; Peterson, Russell ; Pitt, Sidney ; Schieven, Gary L ; Schmidt, Robert J ; Tokarski, John ; Wen, Mei-Li ; Wityak, John ; Borzilleri, Robert M

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6658-6661 [Periódico revisado por pares]

United States: American Chemical Society

Texto completo disponível