Idioma:

A multivariate analysis of prognostic factors in early stage hodgkin's disease

Tubiana, M ; Henry-Amar, M ; Van Der Werf-Messing, B ; Henry, J ; Abbatucci, J ; Burgers, M ; Hayat, M ; Somers, R ; Laugier, A ; Carde, P

Int. J. Radiat. Oncol., Biol. Phys.; (United States), 1985, Vol.11 (1), p.23-30 [Periódico revisado por pares]

New York, NY: Elsevier Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
A multivariate analysis of prognostic factors in early stage hodgkin's disease
Autor: Tubiana, M ; Henry-Amar, M ; Van Der Werf-Messing, B ; Henry, J ; Abbatucci, J ; Burgers, M ; Hayat, M ; Somers, R ; Laugier, A ; Carde, P
Assuntos: 550603 - Medicine- External Radiation in Therapy- (1980-) ; 560151 - Radiation Effects on Animals- Man ; Adult ; AGE DEPENDENCE ; Age Factors ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Biological and medical sciences ; Clinical Trials as Topic ; Combined Modality Therapy ; DISEASES ; EXTERNAL IRRADIATION ; Factor Analysis, Statistical ; Female ; Hematologic and hematopoietic diseases ; HISTOLOGY ; Hodgkin Disease - drug therapy ; Hodgkin Disease - mortality ; Hodgkin Disease - pathology ; Hodgkin Disease - radiotherapy ; Hodgkin's disease ; HODGKINS DISEASE ; Humans ; IRRADIATION ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; LYMPH NODES ; Lymph Nodes - pathology ; Lymph Nodes - radiation effects ; LYMPHATIC SYSTEM ; LYMPHOMAS ; Male ; MATHEMATICS ; Mediastinal Neoplasms - pathology ; Medical sciences ; MEDICINE ; Middle Aged ; MULTIVARIATE ANALYSIS ; Neoplasm Staging ; NEOPLASMS ; NUCLEAR MEDICINE ; PARTIAL BODY IRRADIATION ; PATHOGENESIS ; PATIENTS ; Prognosis ; Prognostic factors ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Random Allocation ; Recurrence ; SEX DEPENDENCE ; Sex Factors ; SIDE EFFECTS ; Splenic Neoplasms - pathology ; STATISTICS ; SURVIVAL TIME ; THERAPY
É parte de: Int. J. Radiat. Oncol., Biol. Phys.; (United States), 1985, Vol.11 (1), p.23-30
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Descrição: A multivariate analysis of the prognostic factors was carried out with a Cox model on 1,139 patients with clinical Stage I + II Hodgkin's disease included in three controlled clinical trials. The following indicators had been prospectively registered: age, sex, systemic symptoms, erythrocyte sedimentation rate (ESR), number and sites of involved lymph node areas, histologic type, clinical stage, pattern of presentation, results of staging laparotomy when performed, as well as the date and type of treatment. A linear logistic analysis showed that most of the indicators are interrelated. This emphasizes the necessity of a multivariate analysis in order to assess the independent influence of each of them. The two main prognostic indicators for relapse-free survival are systemic symptoms and/or ESR and number of involved areas. The only significant factor for survival after relapse is age. Sex has a small but significant influence on relapse-free survival. The relative influence of each indicator varies with the type of treatment and these variations may help in understanding the biologic significance of the indicators.
Editor: New York, NY: Elsevier Inc
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

A multivariate analysis of prognostic factors in early stage hodgkin's disease

Tubiana, M ; Henry-Amar, M ; Van Der Werf-Messing, B ; Henry, J ; Abbatucci, J ; Burgers, M ; Hayat, M ; Somers, R ; Laugier, A ; Carde, P

New York, NY: Elsevier Inc

Buscando em bases de dados remotas. Favor aguardar.