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A clinical analysis of 32 cases of POEMS syndrome

Zhu, Wei-guo ; Wang, Yu ; Zeng, Xue-jun ; Wang, Qiang ; Shen, Ti

Chung-hua nei kʿo tsa chih, 2006-02, Vol.45 (2), p.108

China

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  • Título:
    A clinical analysis of 32 cases of POEMS syndrome
  • Autor: Zhu, Wei-guo ; Wang, Yu ; Zeng, Xue-jun ; Wang, Qiang ; Shen, Ti
  • Assuntos: Adult ; Aged ; Biopsy ; Bone Marrow - pathology ; Female ; Humans ; Immunoelectrophoresis ; Immunohistochemistry ; Male ; Middle Aged ; Myeloma Proteins - analysis ; POEMS Syndrome - diagnosis ; Retrospective Studies ; Sensitivity and Specificity
  • É parte de: Chung-hua nei kʿo tsa chih, 2006-02, Vol.45 (2), p.108
  • Descrição: To compare the clinical features of POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes) syndrome patients from Peking Union Medical College Hospital (PUMCH) with those of patients in previous reports. Thirty-two patients with POEMS syndrome were identified in PUMCH over the last two decades. The clinical features of these patients were compared with those in other large series from Japan, China, and the United States. The average age at presentation was 45.8 years; 22 were men. All 32 patients had polyneuropathy and decreased knee-jerk reflex. Organomegaly was present in 31 patients. Nine patients underwent lymph node biopsy and 5 of them were proven to have Castleman's disease. Twenty-six patients had at least one endocrine abnormality at time of presentation, not including more commonly prevalent diseases like diabetes mellitus or hypothyroidism. Seventy-two percent (18/25) of the patients had a detectable monoclonal protein with serum immunofixation, but only 16.7% (4/24) had p
  • Editor: China
  • Idioma: Chinês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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