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Opsonizing and agglutinating antibodies against Plasmodium falciparum schizont-infected erythrocytes in Gambian sera

Abdalla, S.H.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Vol.81 (2), p.214-218 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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Título:
Opsonizing and agglutinating antibodies against Plasmodium falciparum schizont-infected erythrocytes in Gambian sera
Autor: Abdalla, S.H.
Assuntos: Adult ; Biological and medical sciences ; Erythrocytes - immunology ; Erythrocytes - parasitology ; Hemagglutination ; Human protozoal diseases ; Humans ; Immunoglobulin G - analysis ; Infectious diseases ; Malaria ; Malaria - immunology ; Medical sciences ; Opsonin Proteins - analysis ; Parasitic diseases ; Phagocytosis ; Plasmodium falciparum ; Plasmodium falciparum - immunology ; Protozoal diseases ; Rosette Formation ; Tropical medicine
É parte de: Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Vol.81 (2), p.214-218
Notas: ark:/67375/HXZ-Q3P53DF3-9
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Descrição: The presence of an IgG antibody to autologous schizont-infected red blood cells (SIRBC) in the sera of Gambian children with acute malaria and a positive direct anti-globulin test (DAT) was demonstrated by two methods: IgG quantitation using 125I-labelled anti-IgG and phagocytosis of these SIRBC. A similar antibody could not be demonstrated in sera of children with acute malaria and a negative DAT. When a laboratory strain of parasite was used there was a more variable pattern of IgG uptake but the highest was from sera of immune adult Gambians and Gambian children with acute malaria and a positive DAT. The uptake of IgG by SIRBC may be a useful test to determine the specificities of antibodies against different isolates of P. falciparum.
Editor: Oxford: Elsevier Ltd
Idioma: Inglês

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Opsonizing and agglutinating antibodies against Plasmodium falciparum schizont-infected erythrocytes in Gambian sera

Abdalla, S.H.

Oxford: Elsevier Ltd

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