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Emerging Role for Mammalian Target of Rapamycin in Male Fertility

Oliveira, Pedro F ; Cheng, C.Y ; Alves, Marco G

Trends in endocrinology and metabolism, 2017-03, Vol.28 (3), p.165-167 [Periódico revisado por pares]

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Título:
Emerging Role for Mammalian Target of Rapamycin in Male Fertility
Autor: Oliveira, Pedro F ; Cheng, C.Y ; Alves, Marco G
Assuntos: Endocrinology & Metabolism ; fertility ; Humans ; Infertility, Male - metabolism ; Male ; mTOR ; Sertoli cell ; Sertoli Cells - metabolism ; Signal Transduction - genetics ; Signal Transduction - physiology ; spermatogenesis ; Spermatogenesis - genetics ; Spermatogenesis - physiology ; TOR Serine-Threonine Kinases - genetics ; TOR Serine-Threonine Kinases - metabolism
É parte de: Trends in endocrinology and metabolism, 2017-03, Vol.28 (3), p.165-167
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: Male fertility is modulated by environmental, endocrine, paracrine, and metabolic cues. Mammalian target of rapamycin (mTOR) coordinates many cellular events in response to those signals. Here, we discuss how the mTOR pathway integrates and mediates signals throughout the male reproductive system, acting as a central player in the control of spermatogenesis.
Editor: United States: Elsevier Ltd
Idioma: Inglês

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