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Vaccination with recombinant Clostridium perfringens toxoids α and β promotes elevated antepartum and passive humoral immunity in swine

Salvarani, Felipe M ; Conceição, Fabricio R ; Cunha, Carlos E.P ; Moreira, Gustavo M.S.G ; Pires, Prhiscylla S ; Silva, Rodrigo O.S ; Alves, Guilherme G ; Lobato, Francisco C.F

Vaccine, 2013-08, Vol.31 (38), p.4152-4155 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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Título:
Vaccination with recombinant Clostridium perfringens toxoids α and β promotes elevated antepartum and passive humoral immunity in swine
Autor: Salvarani, Felipe M ; Conceição, Fabricio R ; Cunha, Carlos E.P ; Moreira, Gustavo M.S.G ; Pires, Prhiscylla S ; Silva, Rodrigo O.S ; Alves, Guilherme G ; Lobato, Francisco C.F
Assuntos: Adjuvants ; Allergy and Immunology ; Alpha toxin ; animal production ; Animals ; Animals, Newborn ; anti-infective agents ; Antibodies, Neutralizing ; antigens ; antitoxins ; Applied microbiology ; Bacterial Vaccines - genetics ; Bacterial Vaccines - immunology ; Bacterial Vaccines - pharmacology ; Beta toxin ; Biological and medical sciences ; blood serum ; Clostridium Infections - prevention & control ; Clostridium Infections - veterinary ; Clostridium perfringens ; diarrhea ; Diarrhea - microbiology ; Diarrhea - prevention & control ; Diarrhea - veterinary ; Escherichia coli ; Escherichia coli - genetics ; Female ; Fundamental and applied biological sciences. Psychology ; humoral immunity ; immune response ; Immunity, Humoral - immunology ; Immunization, Passive ; Microbiology ; Neonatal pig diarrhea ; neutralizing antibodies ; Passive immunity ; piglets ; Pregnancy ; production technology ; Rabbits ; recombinant proteins ; Recombinant vaccine ; sows ; Swine ; Swine Diseases - immunology ; Swine Diseases - prevention & control ; toxoids ; Toxoids - genetics ; Toxoids - immunology ; Treatment Outcome ; vaccination ; vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
É parte de: Vaccine, 2013-08, Vol.31 (38), p.4152-4155
Notas: http://dx.doi.org/10.1016/j.vaccine.2013.06.094
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Descrição: Highlights • Development of a bivalent vaccine against alpha and beta toxin from C. perfringens. • Both recombinant toxins showed reduced or nontoxic activity. • Vaccinated sows produced high levels of neutralizing antibodies. • Passive immunity though colostrum consumption was achieved in piglets. • Assisted colostrum feeding resulted in homogeneous antibody titers in piglets’ sera.
Editor: Kidlington: Elsevier Ltd
Idioma: Inglês

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Vaccination with recombinant Clostridium perfringens toxoids α and β promotes elevated antepartum and passive humoral immunity in swine

Salvarani, Felipe M ; Conceição, Fabricio R ; Cunha, Carlos E.P ; Moreira, Gustavo M.S.G ; Pires, Prhiscylla S ; Silva, Rodrigo O.S ; Alves, Guilherme G ; Lobato, Francisco C.F

Kidlington: Elsevier Ltd

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