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Prolonged immobilization-induced stress delays alveolar bone healing a histometric study in rats

K. F. Bombonato Prado Teresa Lúcia Lamano Carvalho; Janete Aparecida Anselmo-Franci; Luiz Guilherme Brentegani

Histology and Histopathology Murcia v. 16, p. 481-485, 2001

Murcia 2001

Localização: FORP - Fac. Odont. de Ribeirão Preto    (pcd 1225576 )(Acessar)

  • Título:
    Prolonged immobilization-induced stress delays alveolar bone healing a histometric study in rats
  • Autor: K. F. Bombonato Prado
  • Teresa Lúcia Lamano Carvalho; Janete Aparecida Anselmo-Franci; Luiz Guilherme Brentegani
  • Assuntos: ESTRESSE PSICOLÓGICO; RATOS; PATOLOGIA BUCAL; HISTOLOGIA ORAL
  • É parte de: Histology and Histopathology Murcia v. 16, p. 481-485, 2001
  • Descrição: The purpose of the present study was to investigate the effect of prolonged immobilization-induced stress on reparative bone formation, using the rat alveolar healing as an experimental protocol. Stress was attained by immobilization for 2 hours a day, beginning three days before extraction of the upper right incisors and continuing until sacrifice. The stress condition was assayed on the basis of plasma corticosterone concentration (measured by double-antibody radioimmunoassay), which increased by 2.5 to 4 times in rats submitted to immobilization. The volume density of neoformed bone filling the alveolar socket was quantified by a histometric differential point-counting method 7 to 21 days following tooth extraction. Stress caused a significant delay in reparative bone increment, somewhat related to impairment of coagulum remission and/or organization
  • Editor: Murcia
  • Data de criação/publicação: 2001
  • Formato: p. 481-485.
  • Idioma: Inglês

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