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Augmented Muscle Vasodilatory Responses in Obese Children With Glu27 Beta 2-Adrenoceptor Polymorphism

Alexandre G. da Silva Mauricio M Ribeiro; Ivani C Trombetta; Christiane Nicolau; Eliana Frazzatto; Isabel Guazzelli Matos,Luciana N. J.; Alfredo Halpern; C. E Negrão (Carlos Eduardo); Sandra M.F Villares

Pediatric Exercise Science Champaign v. 20, n. 2, p. 157-168, mai. 2008

Champaign 2008

Acesso online. A biblioteca também possui exemplares impressos.

  • Título:
    Augmented Muscle Vasodilatory Responses in Obese Children With Glu27 Beta 2-Adrenoceptor Polymorphism
  • Autor: Alexandre G. da Silva
  • Mauricio M Ribeiro; Ivani C Trombetta; Christiane Nicolau; Eliana Frazzatto; Isabel Guazzelli Matos,Luciana N. J.; Alfredo Halpern; C. E Negrão (Carlos Eduardo); Sandra M.F Villares
  • Assuntos: POLIMORFISMO; OBESIDADE; CRIANÇAS; FISIOLOGIA DO EXERCÍCIO
  • É parte de: Pediatric Exercise Science Champaign v. 20, n. 2, p. 157-168, mai. 2008
  • Notas: Disponível: http://www.humankinetics.com/PES/viewarticle.cfm?aid=15796
  • Descrição: This study examined forearm vasodilatation during mental challenge and exercise in 72 obese children (OC; age = 10 ´+OU-´ 0.1 years) homozygous with polymorphism in the allele 27 of the ´beta´2-adrenoceptors: Gln27 (n = 61) and Glu27 (n = 11). Forearm blood flow was recorded during 3 min of each using the Stroop color-word test (MS) and handgrip isometric exercise. Baseline hemodynamic and vascular measurements were similar. During the MS, peak forearm vascular conductance was significantly greater in group Glu27 (´delta´ = 0.35 ´+OU-´ 0.4 vs. 0.12 ´+OU-´ 0.1 units, respectively, p = .042). Similar results were found during exercise (´delta´ = 0.64 ´+OU-´ 0.1 vs. 0.13 ´+OU-´ 0.1 units, respectively, p = .035). Glu27 OC increased muscle vasodilatory responsiveness upon the MS and exercise
  • Editor: Champaign
  • Data de criação/publicação: 2008
  • Formato: p. 157-168.
  • Idioma: Inglês

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