Idioma:

Predictors of poor outcome after carotid intervention

Dua, Anahita, MD, MS, MBA ; Romanelli, Michael, BS ; Upchurch, Gilbert R., MD ; Pan, James, MD ; Hood, Douglas, MD ; Hodgson, Kim J., MD ; Desai, Sapan S., MD, PhD, MBA

Journal of vascular surgery, 2016-09, Vol.64 (3), p.663-670 [Periódico revisado por pares]

United States: Elsevier Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
Predictors of poor outcome after carotid intervention
Autor: Dua, Anahita, MD, MS, MBA ; Romanelli, Michael, BS ; Upchurch, Gilbert R., MD ; Pan, James, MD ; Hood, Douglas, MD ; Hodgson, Kim J., MD ; Desai, Sapan S., MD, PhD, MBA
Assuntos: Angioplasty - adverse effects ; Angioplasty - economics ; Angioplasty - instrumentation ; Angioplasty - mortality ; Asymptomatic Diseases ; Carotid Artery Diseases - complications ; Carotid Artery Diseases - economics ; Carotid Artery Diseases - mortality ; Carotid Artery Diseases - therapy ; Chi-Square Distribution ; Cost-Benefit Analysis ; Databases, Factual ; Endarterectomy, Carotid - adverse effects ; Endarterectomy, Carotid - economics ; Endarterectomy, Carotid - mortality ; Health Care Costs ; Hospital Mortality ; Hospitals, Low-Volume ; Humans ; Ischemic Attack, Transient - etiology ; Logistic Models ; Multivariate Analysis ; Odds Ratio ; Postoperative Complications - etiology ; Postoperative Complications - mortality ; Propensity Score ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Sex Factors ; Stents ; Stroke - etiology ; Surgery ; Time Factors ; Treatment Outcome ; United States
É parte de: Journal of vascular surgery, 2016-09, Vol.64 (3), p.663-670
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Background A variety of patient factors are known to adversely impact outcomes after carotid endarterectomy (CEA) or carotid artery stenting (CAS). However, their specific impact on complications and mortality and how they differ between CEA and CAS is unknown. The purpose of this study is to identify patient and hospital factors that adversely impact outcomes. Methods Patients who underwent CEA or CAS between 1998 and 2012 (N = 1,756,445) were identified using the Agency for Healthcare Research and Quality National Inpatient Sample and State Ambulatory Services Databases. A multivariate analysis was completed to evaluate the impact of demographics, patient factors, type of symptoms (transient ischemic attack or cerebrovascular accident), volume of cases (3 per year vs 1-2 interventions), and interventions upon outcomes, perioperative complications (stroke, myocardial infarction, and bleeding), duration of stay, inpatient mortality, and cost. Significant factors were then used as part of a multivariate regression analysis to determine odds ratios. A subgroup analysis using propensity matching evaluating 1:1 risk-matched asymptomatic and symptomatic patients was completed. Patient cohorts were matched on the basis of Charlson scores. Results Over the study period a total of 1,583,614 asymptomatic CEA, 7317 asymptomatic CAS, 162,362 symptomatic CEA, and 3149 symptomatic CAS patients were included. Symptomatic disease portends a worse outlook after either CEA or CAS. Costs of the procedure increased with complications with stroke adding the most significant cost burden. For risk-matched asymptomatic and symptomatic patients, female gender ( P < .001) and performing one or two cases per year ( P < .05) were associated with higher cerebrovascular accident risk. In asymptomatic and symptomatic patients, predictors of myocardial infarction included congestive heart failure ( P < .001) and peripheral artery disease ( P < .05) and predictors of bleeding included peripheral artery disease ( P < .05) and chronic obstructive pulmonary disease ( P < .01) for symptomatic patients only. For both asymptomatic and symptomatic patients, predictors of mortality included female gender ( P < .001) and performing one or two cases per year ( P < .01). Female gender was one of the strongest overall predictors of adverse outcome after CAS (odds ratio, 21.39 for death; P < .001). Low volume (<3 cases per year per practitioner) is a predictor of adverse outcome after CAS only. Conclusions Higher rates of postoperative stroke and inpatient mortality for women undergoing CAS is an unexpected finding, and may indicate that this population is vulnerable to complications after endovascular management. Low volume is a predictor of complications and subsequent mortality primarily for CAS. Patients who undergo CEA continue to have superior outcomes compared with matched cohorts who undergo CAS.
Editor: United States: Elsevier Inc
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 9 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Predictors of poor outcome after carotid intervention

Dua, Anahita, MD, MS, MBA ; Romanelli, Michael, BS ; Upchurch, Gilbert R., MD ; Pan, James, MD ; Hood, Douglas, MD ; Hodgson, Kim J., MD ; Desai, Sapan S., MD, PhD, MBA

United States: Elsevier Inc

Buscando em bases de dados remotas. Favor aguardar.