Idioma:

Retinal functional development is sensitive to environmental enrichment: a role for BDNF

Landi, S ; Sale, A ; Berardi, N ; Viegi, A ; Maffei, L ; Cenni, M.C

The FASEB journal, 2007, Vol.21 (1), p.130-139 [Periódico revisado por pares]

United States: The Federation of American Societies for Experimental Biology

Texto completo disponível

Citações Citado por

Enviar para

Título:
Retinal functional development is sensitive to environmental enrichment: a role for BDNF
Autor: Landi, S ; Sale, A ; Berardi, N ; Viegi, A ; Maffei, L ; Cenni, M.C
Assuntos: Animals ; Base Sequence ; brain derived neurotrophic factor ; Brain-Derived Neurotrophic Factor - physiology ; DNA Primers ; Electroretinography ; Enzyme-Linked Immunosorbent Assay ; Evoked Potentials, Visual ; Female ; Immunohistochemistry ; Male ; pattern electroretinogram ; Pregnancy ; Rats ; Rats, Long-Evans ; retina ; Retina - growth & development ; Retina - physiology ; Visual Acuity
É parte de: The FASEB journal, 2007, Vol.21 (1), p.130-139
Notas: http://www.fasebj.org/
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Retina has long been considered less plastic than cortex or hippocampus, the very sites of experience-dependent plasticity. Now, we show that retinal development is responsive to the experience provided by an enriched environment (EE): the maturation of retinal acuity, which is a sensitive index of retinal circuitry development, is strongly accelerated in EE rats. This effect is present also in rats exposed to EE up to P10, that is before eye opening, suggesting that factors sufficient to trigger retinal acuity development are affected by EE during the first days of life. Brain derived neurotrophic factor (BDNF) is precociously expressed in the ganglion cell layer of EE with respect to non-EE rats and reduction of BDNF expression in EE animals counteracts EE effects on retinal acuity. Thus, EE controls the development of retinal circuitry, and this action depends on retinal BDNF expression.--Landi, S., Sale, A., Berardi, N., Viegi, A., Maffei, L., Cenni, M. C. Retinal functional development is sensitive to environmental enrichment: a role for BDNF.
Editor: United States: The Federation of American Societies for Experimental Biology
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Retinal functional development is sensitive to environmental enrichment: a role for BDNF

Landi, S ; Sale, A ; Berardi, N ; Viegi, A ; Maffei, L ; Cenni, M.C

United States: The Federation of American Societies for Experimental Biology

Buscando em bases de dados remotas. Favor aguardar.