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Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States

Ray, Evan L ; Lopez, Velma K ; Bracher, Johannes ; Brennen, Andrea ; Castro Rivadeneira, Alvaro J ; Gerding, Aaron ; Khandelwal, Ayush ; Mühlemann, Anja ; Gu, Youyang ; Jain, Sansiddh ; Bannur, Nayana ; Raval, Alpan ; Dahan, Maytal ; Gaither, Kelly ; Scott, James G ; Tec, Mauricio ; Cegan, Jeffrey C ; Dettwiller, Ian D ; Lafferty, Brandon ; Parno, Matthew D ; Trump, Benjamin D ; Faraone, Stephen V ; Morley, Christopher P ; Wang, Dongliang ; Corsetti, Sabrina M ; Eisenberg, Marisa C ; Yu, Rose ; Zhao, Yanting ; Wang, Lingxiao ; Xu, Pan ; Zhang, Weitong ; Lega, Joceline ; Guertin, Stephanie L ; Turner, Stephen D ; Hong, Qi-Jun ; Kong, Stanley ; Koyluoglu, Ugur ; Kyriakides, Christina ; Nirgudkar, Ninad ; Ozcan, Gokce ; Siegel, Daniel ; Stiefeling, Chris ; Wong, Alexander ; Moore, Sean ; Oidtman, Rachel ; Gao, Zhifeng ; Cao, Wei ; Li, Chaozhuo ; Liu, Tie-Yan ; Zheng, Shun ; Vespignani, Alessandro ; Baek, Jackie ; Farias, Vivek ; Levi, Retsef ; Wilde, Joshua ; Nze-Ndong, David ; Spantidakis, Ioannis ; Thayaparan, Leann ; Wolfinger, Russ ; Fairchild, Geoffrey ; Wilson, Shelby ; Kaminsky, Joshua ; Kaminsky, Kathryn ; Lemaitre, Joseph C ; Burant, John C ; Wang, Lily ; Gao, Lei ; Kim, Myungjin ; Reiner, Robert C ; Barber, Ryan ; Hay, Simon I ; Gurung, Heidi L ; Stage, Steven A ; Adhikari, Bijaya ; Cui, Jiaming ; Tabassum, Anika ; Asplund, John ; Serban, Nicoleta ; Arik, Sercan O ; Epshteyn, Arkady ; Kanal, Elli ; Li, Chun-Liang ; Sava, Dario ; Abbott, Sam ; Hellewell, Joel ; Skali Lami, Omar ; Soni, Saksham ; Adee, Madeline ; Zeng, Donglin ; Green, Alden ; Bien, Jacob ; Hu, Addison J ; McDonald, Daniel ; Narasimhan, Balasubramanian ; Tibshirani, Rob ; Ventura, Valerie ; O'Dea, Eamon B ; Pagano, Robert ; Slayton, Rachel B ; Johansson, Michael A

Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (15), p.e2113561119 [Periódico revisado por pares]

United States: National Academy of Sciences

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Título:
Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States
Autor: Ray, Evan L ; Lopez, Velma K ; Bracher, Johannes ; Brennen, Andrea ; Castro Rivadeneira, Alvaro J ; Gerding, Aaron ; Khandelwal, Ayush ; Mühlemann, Anja ; Gu, Youyang ; Jain, Sansiddh ; Bannur, Nayana ; Raval, Alpan ; Dahan, Maytal ; Gaither, Kelly ; Scott, James G ; Tec, Mauricio ; Cegan, Jeffrey C ; Dettwiller, Ian D ; Lafferty, Brandon ; Parno, Matthew D ; Trump, Benjamin D ; Faraone, Stephen V ; Morley, Christopher P ; Wang, Dongliang ; Corsetti, Sabrina M ; Eisenberg, Marisa C ; Yu, Rose ; Zhao, Yanting ; Wang, Lingxiao ; Xu, Pan ; Zhang, Weitong ; Lega, Joceline ; Guertin, Stephanie L ; Turner, Stephen D ; Hong, Qi-Jun ; Kong, Stanley ; Koyluoglu, Ugur ; Kyriakides, Christina ; Nirgudkar, Ninad ; Ozcan, Gokce ; Siegel, Daniel ; Stiefeling, Chris ; Wong, Alexander ; Moore, Sean ; Oidtman, Rachel ; Gao, Zhifeng ; Cao, Wei ; Li, Chaozhuo ; Liu, Tie-Yan ; Zheng, Shun ; Vespignani, Alessandro ; Baek, Jackie ; Farias, Vivek ; Levi, Retsef ; Wilde, Joshua ; Nze-Ndong, David ; Spantidakis, Ioannis ; Thayaparan, Leann ; Wolfinger, Russ ; Fairchild, Geoffrey ; Wilson, Shelby ; Kaminsky, Joshua ; Kaminsky, Kathryn ; Lemaitre, Joseph C ; Burant, John C ; Wang, Lily ; Gao, Lei ; Kim, Myungjin ; Reiner, Robert C ; Barber, Ryan ; Hay, Simon I ; Gurung, Heidi L ; Stage, Steven A ; Adhikari, Bijaya ; Cui, Jiaming ; Tabassum, Anika ; Asplund, John ; Serban, Nicoleta ; Arik, Sercan O ; Epshteyn, Arkady ; Kanal, Elli ; Li, Chun-Liang ; Sava, Dario ; Abbott, Sam ; Hellewell, Joel ; Skali Lami, Omar ; Soni, Saksham ; Adee, Madeline ; Zeng, Donglin ; Green, Alden ; Bien, Jacob ; Hu, Addison J ; McDonald, Daniel ; Narasimhan, Balasubramanian ; Tibshirani, Rob ; Ventura, Valerie ; O'Dea, Eamon B ; Pagano, Robert ; Slayton, Rachel B ; Johansson, Michael A
Assuntos: 60 APPLIED LIFE SCIENCES ; Biological Sciences ; Coronaviruses ; COVID-19 ; COVID-19 - mortality ; Data Accuracy ; Decision making ; ensemble forecast ; Fatalities ; Forecasting ; Health care ; Horizon ; Humans ; Mathematical models ; Medical supplies ; Model accuracy ; model evaluation ; Modelling ; Pandemics ; Physical Sciences ; Predictions ; Probability ; Public health ; Public Health - trends ; Teams ; United States - epidemiology
É parte de: Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (15), p.e2113561119
Notas: 89233218CNA000001
LA-UR-21-20490
USDOE Laboratory Directed Research and Development (LDRD) Program: National Science Foundation (NSF)
Edited by Kenneth Wachter, University of California, Berkeley, CA; received July 24, 2021; accepted January 24, 2022
Author contributions: E.Y.C., E.L.R., V.K.L., J. Bracher, T.G., K.H.H., Y.H., K.L., J.N., J. White, R.B.S., M.A.J., M. Biggerstaff, and N.G.R. designed research; E.Y.C., E.L.R., J. Bracher, A.J.C.R., A.G., K.H.H., Y.H., D.J., A.H.K., A.K., K.L., A.M., J.N., A. Shah, A. Stark, Y. Wang, N.W., M.W.Z., and N.G.R. performed research; J. Bracher, A. Brennen, T.G., Y.G., S.J., N.B., A.D., M. Kulkarni, S. Merugu, A.R., S. Shingi, A. Tiwari, J. White, N.F.A., S. Woody, M. Dahan, S. Fox, K.G., M.L., L.A.M., J.G.S., M.T., A. Srivastava, G.E.G., J.C.C., I.D.D., W.P.E., M.W.F., R.H.H., B.L., I.L., M.L.M., M.D.P., M.A.R., B.D.T., Y.Z.-J., S. Chen, S.V.F., J. Hess, C.P.M., A. Salekin, D. Wang, S.M.C., T.M.B., M.C.E., K.F., Y.H., E.T.M., E.M., R.L.M., T.S., D. Sheldon, G.C.G., R.Y., Liyao Gao, Y.M., D. Wu, X.Y., X.J., Y.-X.W., Y.C., Lihong Guo, Y.Z., Q.G., J. Chen, Lingxiao Wang, P.X., W.Z., D. Zou, H.B., J. Lega, S. McConnell, V.P.N., S.L.G., C.H.-L., S.D.T., Y.S., X.B., R. Walraven, Q.-J.H., S.K., A. van de Walle, J.A.T., M.B.-N., S. Riley, P.R., U.K., D.D., P.F., B.H., C.K., H.L., J. Milliken, M. Moloney, J. Morgan, N.N., G.O., N. Piwonka, M. Ravi, C. Schrader, E.S., D. Siegel, R. Spatz, C. Stiefeling, B.W., A.W., S. Cavany, G.E., S. Moore, R.O., A. Perkins, D. Kraus, A.K., Z. Gao, J. Bian, W.C., J.L.F., C. Li, T.-Y.L., X. Xie, S. Zhang, S. Zheng, A.V., M.C., J.T.D., K.M., A.P., X. Xiong, A.Z., J. Baek, V.F., A. Georgescu, R.L., D. Sinha, J. Wilde, G.P., M.A.B., D.N.-N., D. Singhvi, I.S., L.T., A. Tsiourvas, A. Sarker, A.J., D. Shah, N.D.P., L.A.C., S. Sundar, R.W., D.O., L.C., G.F., I.M., D.K., M. Kinsey, L.C.M., K.R.-L., L.S., K.T., S. Wilson, E.C.L., J. Dent, K.H.G., A.L.H., J.K., K.K., L.T.K., S.A.L., J.C.L., J.L., H.R.M., J.P.-S., S. Shah, C.P.S., S.A.T., J. Wills, M. Marshall, L. Gardner, K.N., J.C.B., Lily Wang, L.G., Z. Gu, M. Kim, X.L., G.W., Y. Wang, S.Y., R.C.R., R.B., E.G., S.I.H., S.L., C.M., D.P., H.L.G., P.B., S.A.S., B.T.S., B.A.P., B.A., J. Cui, A. Rodríguez, A.T., J. Xie, P.K., J.A., A. Baxter, B.E.O., N. Serban, S.O.A., M. Dusenberry, A.E., E.K., L.T.L., C.-L.L., T.P., D. Sava, R.S., T.T., N.Y., J.Y., L.Z., S.A., N.I.B., S. Funk, J. Hellewell, S.R.M., K.S., M.Z., R.K., T.K.Y., S.P., J. Shaman, M.L.L., D.B., O.S.L., S. Soni, H.T.B., T.A., M.A., J. Chhatwal, O.O.D., M.A.L., B.P.L., P.M., J. Xiao, Y. Wang, Q.W., S.X., D. Zeng, A. Green, J. Bien, L.B., A.J.H., M.J., D.M., B.N., C.P., S. Rajanala, A. Rumack, N. Simon, R.J.T., R.T., V.V., L. Wasserman, E.B.O., J.M.D., R.P., Q.T.T., L.S.T.H., H.H., and N.G.R. contributed new reagents/analytic tools; E.Y.C., E.L.R., J. Bracher, A. Gerding, Y.H., K.L., and N.G.R. analyzed data; and E.Y.C., E.L.R., V.K.L., J. Bracher, and N.G.R. wrote the paper.
Descrição: Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks.
Editor: United States: National Academy of Sciences
Idioma: Inglês

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Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States

United States: National Academy of Sciences

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