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Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

Leon, Martin B ; Smith, Craig R ; Mack, Michael ; Miller, D. Craig ; Moses, Jeffrey W ; Svensson, Lars G ; Tuzcu, E. Murat ; Webb, John G ; Fontana, Gregory P ; Makkar, Raj R ; Brown, David L ; Block, Peter C ; Guyton, Robert A ; Pichard, Augusto D ; Bavaria, Joseph E ; Herrmann, Howard C ; Douglas, Pamela S ; Petersen, John L ; Akin, Jodi J ; Anderson, William N ; Wang, Duolao ; Pocock, Stuart

The New England journal of medicine, 2010-10, Vol.363 (17), p.1597-1607 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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Título:
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Autor: Leon, Martin B ; Smith, Craig R ; Mack, Michael ; Miller, D. Craig ; Moses, Jeffrey W ; Svensson, Lars G ; Tuzcu, E. Murat ; Webb, John G ; Fontana, Gregory P ; Makkar, Raj R ; Brown, David L ; Block, Peter C ; Guyton, Robert A ; Pichard, Augusto D ; Bavaria, Joseph E ; Herrmann, Howard C ; Douglas, Pamela S ; Petersen, John L ; Akin, Jodi J ; Anderson, William N ; Wang, Duolao ; Pocock, Stuart
Assuntos: Aged ; Aged, 80 and over ; Aortic valve stenosis ; Aortic Valve Stenosis - mortality ; Aortic Valve Stenosis - surgery ; Aortic Valve Stenosis - therapy ; Biological and medical sciences ; Candidates ; Cardiac Catheterization ; Cardiology. Vascular system ; Cardiovascular disease ; Cardiovascular Diseases - mortality ; Care and treatment ; Catheterization ; Echocardiography ; Endocardial and cardiac valvular diseases ; Female ; General aspects ; Health aspects ; Heart ; Heart Valve Prosthesis Implantation - methods ; Hospitalization ; Humans ; Kaplan-Meier Estimate ; Male ; Medical sciences ; Patient outcomes ; Patients ; Prospective Studies ; Surgery ; Treatment Outcome
É parte de: The New England journal of medicine, 2010-10, Vol.363 (17), p.1597-1607
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-News-2
ObjectType-Feature-3
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Descrição: Patients with aortic stenosis underwent transfemoral transcatheter implantation of a balloon-expandable bovine pericardial aortic valve. One-year mortality was lower with the balloon-expandable valve than with standard therapy, but the risk of stroke was higher. Aortic stenosis is an insidious disease with a long latency period 1 followed by rapid progression after the appearance of symptoms, 2 – 5 resulting in a high rate of death (approximately 50% in the first 2 years after symptoms appear) among untreated patients. 1 , 6 – 8 Surgical replacement of the aortic valve reduces symptoms and improves survival in patients with aortic stenosis, 9 – 11 and in the absence of serious coexisting conditions, the procedure is associated with low operative mortality. 12 , 13 However, in clinical practice, at least 30% of patients with severe symptomatic aortic stenosis do not undergo surgery for replacement of the aortic . . .
Editor: Waltham, MA: Massachusetts Medical Society
Idioma: Inglês

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Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

Waltham, MA: Massachusetts Medical Society

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