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Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities

Chen, Wei-Cheng ; Wang, Shih-Wei ; Li, Cai-Wei ; Lin, Hsiang-Ru ; Yang, Chang-Syun ; Chu, Yi-Cheng ; Lee, Tzong-Huei ; Chen, Jih-Jung

Antioxidants, 2022-02, Vol.11 (2), p.398 [Periódico revisado por pares]

Switzerland: MDPI AG

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Título:
Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities
Autor: Chen, Wei-Cheng ; Wang, Shih-Wei ; Li, Cai-Wei ; Lin, Hsiang-Ru ; Yang, Chang-Syun ; Chu, Yi-Cheng ; Lee, Tzong-Huei ; Chen, Jih-Jung
Assuntos: Acetic acid ; Acetone ; Acids ; Aluminum ; anti-tyrosinase activity ; anti-α-glucosidase activity ; antioxidant activity ; Antioxidants ; Biosynthesis ; Chloroform ; Chronic illnesses ; Diabetes ; Disease ; Enzymes ; Ethanol ; Ethyl acetate ; Fever ; Flavonoids ; Free radicals ; Gastrointestinal diseases ; High-performance liquid chromatography ; Homology ; Hydroxyl radicals ; Inflammation ; Kaempferol ; Liver diseases ; major bioactive components ; Metabolism ; n-Hexane ; Oxidative stress ; Portulaca oleracea ; Potassium ; Quercetin ; Rosmarinic acid ; Solvents ; various solvent extracts ; α-Glucosidase
É parte de: Antioxidants, 2022-02, Vol.11 (2), p.398
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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These authors contributed equally to this work.
Descrição: is a well-known species for traditional medicine and food homology in Taiwan. In traditional medicine, is also used to treat gastrointestinal disorders, liver inflammation, fever, severe inflammation, and headaches. We investigated antioxidant, anti-tyrosinase, and anti-α-glucosidase activities of various solvent extracts and major bioactive components from . Ethanol and acetone extracts showed potent DPPH, ABTS, and hydroxyl radical scavenging activities. Chloroform and -hexane extracts displayed significant superoxide radical scavenging activity. Furthermore, ethyl acetate and acetone extracts of showed potent anti-tyrosinase and anti-α-glucosidase activities. Examined and compared to the various solvent extracts for their chemical compositions using HPLC analysis, we isolated seven major compounds and analyzed their antioxidant, anti-tyrosinase, and anti-α-glucosidase activities. Seven active compounds of , especially quercetin, rosmarinic acid, and kaempferol, exhibited obvious antioxidant, anti-tyrosinase, and anti-α-glucosidase activities. The molecular docking model and the hydrophilic interactive mode of tyrosinase and α-glucosidase revealed that active compounds might have a higher antagonistic effect than commonly inhibitors. Our result shows that the active solvent extracts and their components of have the potential as natural antioxidants, tyrosinase and α-glucosidase inhibitors. Our results suggest that the active solvent extracts of and their components have potential as natural antioxidants, tyrosinase and α-glucosidase inhibitors.
Editor: Switzerland: MDPI AG
Idioma: Inglês

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Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities

Chen, Wei-Cheng ; Wang, Shih-Wei ; Li, Cai-Wei ; Lin, Hsiang-Ru ; Yang, Chang-Syun ; Chu, Yi-Cheng ; Lee, Tzong-Huei ; Chen, Jih-Jung

Switzerland: MDPI AG

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