skip to main content
Idioma:

Spectroscopic and Fluorometric Determination of Cinnarizine and Dipyridamole in Pharmaceutical Tablets Using Eosin Y Dye

Al - Abdali, Zeina ; Saleh, Elham

JOURNAL OF EDUCATION AND SCIENCE, 2013-12, Vol.26 (5), p.173-189 [Periódico revisado por pares]

College of Education for Pure Sciences

Texto completo disponível

Citações Citado por
  • Título:
    Spectroscopic and Fluorometric Determination of Cinnarizine and Dipyridamole in Pharmaceutical Tablets Using Eosin Y Dye
  • Autor: Al - Abdali, Zeina ; Saleh, Elham
  • Assuntos: cinnarizine ; dipyridamole ; eocene y dye ; fluorometric determination ; pharmaceutical tablets ; spectroscopic
  • É parte de: JOURNAL OF EDUCATION AND SCIENCE, 2013-12, Vol.26 (5), p.173-189
  • Descrição: ABSTRACT Spectrophotometric and spectrofluorimetric methods were developed for the determination of cinnarizine and dipyridamole. The spectrophotometric method is based on the formation of ion pair complex  between the studied drugs and eosin Y which shows maximum absorbance at 550 nm in the phthalate buffer (pH3.5) for cinnarazine and 547 nm in citrate buffer (pH3) for dipyridamole. Beerʼs law is obeyed in the concentration ranges of 0.1-8 and  0.1-7 µg/ml with molar absorbitivity values of 4.65×104 and 4.90×104 L.mol-1.cm-1 for cinnarizine and dipyridamole respectively. The spectroflurimetric method is based on the quantitative quenching effect of cinnarizine and dipyridamole on the native fluorescence of eosin Y. The quenching of the fluorescence of eosin Y was measured at 553 nm after excitation at 350 nm. The fluorescence-concentration plot is rectilinear over the ranges of 0.05-5.2 and 0.1-5.0 μg/ml for cinnarizine and dipyridamole respectively. The two proposed methods were successfully applied for the determination of drugs in pharmaceuticals preparations.
  • Editor: College of Education for Pure Sciences
  • Idioma: Inglês;Árabe
Voltar para lista de resultados
Ir para página anteriorAnterior Resultado  2 AvançarIr para próxima página

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.