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Toward Precision Psychiatry in Bipolar Disorder: Staging 2.0

Salagre, Estela ; Dodd, Seetal ; Aedo, Alberto ; Rosa, Adriane ; Amoretti, Silvia ; Pinzon, Justo ; Reinares, Maria ; Berk, Michael ; Kapczinski, Flavio Pereira ; Vieta, Eduard ; Grande, Iria

Frontiers in psychiatry, 2018-11, Vol.9, p.641-641 [Periódico revisado por pares]

Switzerland: Frontiers Research Foundation

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  • Título:
    Toward Precision Psychiatry in Bipolar Disorder: Staging 2.0
  • Autor: Salagre, Estela ; Dodd, Seetal ; Aedo, Alberto ; Rosa, Adriane ; Amoretti, Silvia ; Pinzon, Justo ; Reinares, Maria ; Berk, Michael ; Kapczinski, Flavio Pereira ; Vieta, Eduard ; Grande, Iria
  • Assuntos: Analysis ; Biochemical markers ; biomarkers ; Bipolar disorder ; Care and treatment ; Decision-making ; Genetic aspects ; Manic-depressive illness ; Marcadors bioquímics ; Neurobiology ; personalized psychiatry ; prevention ; Psiquiatria ; Psychiatry ; staging ; Trastorn bipolar
  • É parte de: Frontiers in psychiatry, 2018-11, Vol.9, p.641-641
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
    Reviewed by: Hassan Rahmoune, University of Cambridge, United Kingdom; Yilang Tang, Emory University, United States
    This article was submitted to Molecular Psychiatry, a section of the journal Frontiers in Psychiatry
    Edited by: Johann Steiner, Universitätsklinikum Magdeburg, Germany
  • Descrição: Personalized treatment is defined as choosing the "right treatment for the right person at the right time." Although psychiatry has not yet reached this level of precision, we are on the way thanks to recent technological developments that may aid to detect plausible molecular and genetic markers. At the moment there are some models that are contributing to precision psychiatry through the concept of staging. While staging was initially presented as a way to categorize patients according to clinical presentation, course, and illness severity, current staging models integrate multiple levels of information that can help to define each patient's characteristics, severity, and prognosis in a more precise and individualized way. Moreover, staging might serve as the foundation to create a clinical decision-making algorithm on the basis of the patient's stage. In this review we will summarize the evolution of the bipolar disorder staging model in relation to the new discoveries on the neurobiology of bipolar disorder. Furthermore, we will discuss how the latest and future progress in psychiatry might transform current staging models into precision staging models.
  • Editor: Switzerland: Frontiers Research Foundation
  • Idioma: Inglês
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