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Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles

Carvalho, Luísa C. R. ; Fernandes, Eduarda ; Marques, M. Manuel B.

Chemistry : a European journal, 2011-11, Vol.17 (45), p.12544-12555 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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Título:
Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles
Autor: Carvalho, Luísa C. R. ; Fernandes, Eduarda ; Marques, M. Manuel B.
Assuntos: Amination ; Benzimidazoles - chemical synthesis ; Benzimidazoles - chemistry ; Benzimidazoles - pharmacology ; Catalysis ; Chemistry ; cross-coupling ; Drug Discovery ; Microwaves ; Molecular Structure ; nitrogen heterocycles ; regioselectivity ; synthetic methods
É parte de: Chemistry : a European journal, 2011-11, Vol.17 (45), p.12544-12555
Notas: ark:/67375/WNG-QLXBG2LK-G
istex:A93651EDD77AB0B7D811E63F98B28684A2130958
Fundação para a Ciência e Tecnologia
ArticleID:CHEM201101508
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: 1,2‐Disubstituted benzimidazoles play an important role in several areas and particularly as drug discovery targets. Herein, several methods to assemble these structures are reviewed, from the classical approaches to the more recently developed metal‐catalyzed intramolecular amination process, the cascade arylamination/condensation reaction and polymer‐supported benzimidazole assembly under microwave conditions. From classical to modern: 1,2‐Disubstituted benzimidazoles play an important role in several areas and particularly as drug‐discovery targets. Several methods to assemble these structures are reviewed, from the classical approaches to the more recently developed processes.
Editor: Weinheim: WILEY-VCH Verlag
Idioma: Inglês

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Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles

Carvalho, Luísa C. R. ; Fernandes, Eduarda ; Marques, M. Manuel B.

Weinheim: WILEY-VCH Verlag

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